When you cut an apple and leave it out, it turns brown. Squeeze the apple with lemon juice, an antioxidant, and the process slows down. Simply put, that same “browning” process — known as oxidative stress — happens in the brain as A…
A study led by Research Professor Matej Oreič from VTT Technical Research Centre of Finland suggests that Alzheimer’s disease is preceded by a molecular signature indicative of hypoxia and up-regulated pentose phosphate pathway. This indicator c…
Troy, N.Y. — Researchers at Rensselaer Polytechnic Institute have developed a new method to design antibodies aimed at combating disease. The surprisingly simple process was used to make antibodies that neutralize the harmful protein particles that …
Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study in the December 7 issue of The Journal of Neuroscience. T…
A red dye derived from lichens that has been used for centuries to color fabrics and food appears to reduce the abundance of small toxic protein aggregates in Alzheimer’s disease. The dye, a compound called orcein, and a related substance, called O4, b…
AUGUSTA, Ga. — A diametric shift in the levels of two proteins involved in folding, moving and cutting other proteins enables accumulation of the destructive brain plaque found in Alzheimer’s disease, researchers report.
VPS35 is a protein that fold…
CHICAGO — Northwestern Medicine researchers for the first time have transformed a human embryonic stem cell into a critical type of neuron that dies early in Alzheimer’s disease and is a major cause of memory loss.
This new ability to reprogram …
LA JOLLA, CA — March 3, 2011 — Unexpected results from a Scripps Research Institute and ModGene, LLC study could completely alter scientists’ ideas about Alzheimer’s disease — pointing to the liver instead of the brain as the source of the “am…
ANN ARBOR, Mich.—By mimicking the structure of the silk moth’s antenna, University of Michigan researchers led the development of a better nanopore—a tiny tunnel-shaped tool that could advance understanding of a class of neurodegenerative di…
One in eight Americans will fall prey to Alzheimer’s disease at some point in their life, current statistics say. Because Alzheimer’s is associated with vascular damage in the brain, many of them will succumb through a painful and potentially fatal …
One bad apple is all it takes to spoil the barrel. And one misfolded protein may be all that’s necessary to corrupt other proteins, forming large aggregations linked to several incurable neurodegenerative diseases such as Huntington’s, Parkinson…
