american society for microbiology

First step towards detecting exposure to biowarfare agents

Army researchers are laying the groundwork for what one day could be a test to identify individuals who have been exposed to biological agents. They present their findings today at the American Society for Microbiology’s Biodefense Research Meeting. “Recent events have demonstrated that assessing exposure to a biological threat agent well in advance of onset of illness or at various stages post-exposure would be an important capability to have among the diagnostic options,” says Marti Jett of the Walter Reed Army Institute of Research, the scientist directing the study.

Making a safer anthrax vaccine using spinach

Researchers have developed a strategy for making a safer anthrax vaccine: enlisting the help of spinach plants to manufacture a key component. They report their findings today at the American Society for Microbiology’s Biodefense Research Meeting. “Protective antigen (PA) of Bacillus anthracis is one of the three components of the anthrax toxin,” says Alexander Karasev, a lead researcher on the study. “Purified PA is currently used as a vaccine against anthrax. However, the licensed vaccine derived from apathogenic B. anthracis has side effects and a more efficacious and safer vaccine is needed.”