Genetic link may tie together pesticides, ADHD, Gulf War syndrome

Research at the Salk Institute has identified a gene that may link certain pesticides and chemical weaponry to a number of neurological disorders, including the elusive Gulf War syndrome and attention deficit/hyperactivity disorder (ADHD). The finding is the first to demonstrate a clear genetic link between neurological disorders and exposure to organophosphate chemicals; the gene is one that scientists had not studied in previous efforts to find connections between these chemicals and disease. Organophosphates include household pesticides as well as deadly nerve gases like sarin.

Drug treatment for ADHD sharply cuts risk for future substance abuse

An analysis of all available studies that examine the possible impact of stimulant treatment for attention-deficit hyperactivity disorder (ADHD) on future substance abuse supports the safety of stimulant treatment. Using a statistical technique called meta-analysis, the researchers found that medication treatment for children with ADHD resulted in an almost two-fold reduction in the risk of future substance abuse. “We know that untreated individuals with ADHD are at a significantly increased risk for substance abuse. And we understand why parents often ask whether stimulant medications might lead to future substance abuse among their children,” says Timothy Wilens, MD, MGH director of Substance Abuse Services in Pediatric Psychopharmacology, the paper’s lead author. “Now we can reassure parents and other practitioners that treating ADHD actually protects children against alcohol and drug abuse as well as other future problems.”