COLUMBUS, Ohio — Scientists have found that a synthetic molecule they designed can block activation of a gene in liver cancer cells, halting a process that allows some of those cancer cells to survive chemotherapy.
Without the interference of t…
JUPITER, Fl, October 7, 2010 — Scientists from The Scripps Research Institute have uncovered new evidence that challenges the current theory about a process key to the way modern drugs are designed and how they work in the human body.
The new st…
Biologists have found that a key protein that regulates the biological clocks of mammals also regulates glucose production in the liver and that altering the levels of this protein can improve the health of diabetic mice.
Their discovery, detailed…
Elevated levels of a growth protein in the brains of Alzheimer’s disease (AD) patients is linked to impaired neurogenesis, the process by which new neurons are generated, say researchers at the University of California, San Diego in today’s edit…
St. Jude Children’s Research Hospital investigators have identified a novel structure in cells that serves as a control switch in the body’s system for eliminating damaged cells and also offers new therapeutic potential.
The findings provide fresh…
LA JOLLA, CA — September 9, 2010 — Scientists from The Scripps Research Institute have solved a long-standing mystery of how cells conduct “quality control” to eliminate the toxic effects of a certain kind of error in protein production. The fi…
Elimination of a molecular gatekeeper leads to the development of arthritis in mice, scientists report in a study published in the Journal of Experimental Medicine. The newly discovered gatekeeper is a protein that determines the fate — survival o…
Ames – An Iowa State University team of researchers has developed a type of hybrid proteins that can make double-strand DNA breaks at specific sites in living cells, possibly leading to better gene replacement and gene editing therapies.
Bing …
Westminster, Colo. (August 27, 2010) — Although having a high body mass index (BMI) is a known risk factor for cardiovascular disease, researchers are only beginning to understand how BMI affects the physiological processes involved in the devel…
ANN ARBOR, Mich.—In these lean times, smart consumers refuse to pay a lot for throwaway items, but will shell out a little more for products that can be used again and again. The same is true of bacteria and other microbes, researchers at th…
Using a $225,000 microscope, researchers have identified the key components of a protein called TRIM5α that destroys HIV in rhesus monkeys.
The finding could lead to new TRIM5α-based treatments that would knock out HIV in humans, said se…