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Georgetown University

Clumps of the Parkinson’s protein alpha-synuclein (red) are visible inside neurons (green) in the brain of a mouse. Researchers at Washington University School of Medicine in St. Louis have discovered that the genetic variant APOE4 – long linked to dementia – spurs the spread of harmful clumps of Parkinson’s proteins through the brain. The findings suggest that therapies that target APOE might reduce the risk of dementia for people with Parkinson’s disease.

Vascular defects appear to underlie the progression of Parkinson’s disease

Georgetown University

Categories Brain & Behavior, Health

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