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Washington University in St. Louis

The remains of the most sophisticated prehistoric native civilization north of Mexico are preserved at Cahokia Mounds State Historic Site in Illinois. Archaeologist Natalie Mueller's new study casts doubt on a popular theory about why the ancient city was abandoned.

New study adds to mystery of Cahokia exodus

Categories Social Sciences

Naloxone nasal spray

New Compound Boosts Overdose-Reversing Drug’s Power

Categories Health

Nurse Megan Roberts cares for a COVID-19 patient in an intensive care unit at Barnes-Jewish Hospital in 2020. A study by researchers at Washington University School of Medicine in St. Louis shows that people with COVID-19 who used cannabis were more likely to be hospitalized and require intensive care than those who did not use the drug.

Cannabis Use Linked to Higher Risk of Severe COVID-19

Categories Health

Researchers at Washington University School of Medicine in St. Louis found that pregnant people who took ADHD medications while also being treated for opioid use disorder continued to take medication to address their opioid use disorder about two months longer than patients who stopped taking ADHD medications. These patients also required fewer emergency room visits related to substance use disorder.

ADHD meds may help pregnant patients control opioid use disorder

Categories Brain & Behavior, Health

An illustration depicting a fosa stalking a diademed sifaka lemur in the isolated Betampona Strict Nature Reserve in Madagascar

Lemur’s lament: when one vulnerable species stalks another

Categories Earth, Energy & Environment, Life & Non-humans

A brain scan of a neurofibromatosis type 1 (NF1) patient reveals a tumor on the optic nerve connecting the left eye to the brain (right side of the image). Researchers at Washington University School of Medicine in St. Louis have discovered that an FDA-approved epilepsy drug can prevent or slow the growth of NF1-linked optic gliomas in mice, laying the groundwork for a clinical trial.

Epilepsy drug prevents brain tumors in mice with NF1

Categories Health

Scientists at Washington University School of Medicine in St. Louis have shown that treating mice with an antibody that blocks the interaction between APOE proteins (white) sprinkled within Alzheimer’s disease plaques and the LILRB4 receptor on microglia cells (purple) activates them to clean up damaging plaques (blue) in the brain.

New Alzheimer’s Treatment Shows Promise by Activating Brain’s Immune Cells

Categories Brain & Behavior, Health

infant

Five factors to ensure an infant thrives

Categories Brain & Behavior, Health, Social Sciences

Mice illustration

Life span increases in mice when specific brain cells are activated

Categories Health, Life & Non-humans

Man smoking. Unsplash

Smoking causes brain shrinkage

Categories Brain & Behavior, Health

DNA illustration

Clues to preventing Alzheimer’s come from patient who, despite genetics, evaded disease

Categories Brain & Behavior

Lipid deposits (green) in brain immune cells (red) from mice with Alzheimer’s-like disease all but disappear (right) after the mice are treated with an experimental drug. Researchers at Washington University School of Medicine in St. Louis have found that a form of cholesterol known as cholesteryl esters builds up in the brains of mice with Alzheimer’s-like disease, and that clearing out the cholesteryl esters helps prevent brain damage and behavioral changes.

Lowering a form of brain cholesterol cuts Alzheimer’s-like damage in mice

Categories Brain & Behavior

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