An old pinworm medicine is a new lead in the search for compounds that block a signaling pathway implicated in colon cancer. The findings, reported by Vanderbilt University Medical Center researchers in the November issue of Nature Chemical Biol…
BOSTON – Researchers have identified an important signaling pathway that, when blocked, significantly decreases the spread of pediatric bone cancer.
In their study, researchers at The University of Texas MD Anderson Children’s Cancer Hospital…
WASHINGTON, DC — Researchers at the Center for Neuroscience Research at Children’s National Medical Center have discovered that the two major types of signaling pathways activated during brain cell development — the epidermal growth factor recepto…
COLUMBUS, Ohio — Researchers at the Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James) have identified an experimental agent that targets chronic lymphocytic l…
JUPITER, FL, September 8, 2010 — A team led by a Scripps Research Institute scientist has for the first time identified a new gene that is required for memory formation in Drosophila, the common fruit fly. The gene may have similar functions in …
A key step in understanding the origins of familial breast cancer has
been made by two teams of scientists at the University of California,
Davis. The researchers have purified, for the first time, the protein
produced by the breast cancer suscep…
Skeletal muscles combust both lipids and carbohydrates during exercise. The carbohydrates consist of both glycogen stored in the muscles as well as glucose extracted from the blood. Being a major sink for glucose disposal, skeletal muscle represents…
ANN ARBOR, Mich. — A team of University of Michigan scientists has found that suppressing a newly discovered gene lengthens the lifespan of roundworms. Scientists who study aging have long known that significantly restricting food intake makes an…
Researchers at Dana-Farber Cancer Institute and a team of international collaborators have identified a genetic abnormality that makes ovarian tumor cells initially sensitive to a common chemotherapy agent, cisplatin, and then resistant to the drug over time.
New work by researchers in the Kimmel Cancer Center at Johns Hopkins may allow them to halt the smoking-induced cellular events that lead to 99 percent of all small cell lung cancers (SCLC). The research is reported in the March 5, 2003, issue of Nature. The researchers found that a primitive cellular pathway, called Sonic Hedgehog (named for the cartoon character and spiky hairs it develops on fruit flies) stays turned on long after it should be turned off in some lung cancers.
A strong link exists between lifetime exposure to ultraviolet light, particularly lifetime sunburns, and the development of melanoma ? the most lethal form of skin cancer. Now, for the first time, scientists have identified a specific molecular pathway within cells that becomes mutated by ultraviolet light exposure, thereby speeding up melanoma development.
The slightest turn of the head can significantly change the way a person or animal detects sound. A subtle tilt alters the angle at which high-frequency sound waves hit the ear, providing cues to localize the sound. To use those cues, the brain must put what it hears into the context of the position of the head. Until recently, scientists were not sure how this was done. Now researchers in Wisconsin appear to have the explanation. They have discovered that in the cochlear nucleus, the first sound-processing station in the brain, certain cells accomplish the job by integrating the two kinds of information, each of which travels along a distinct pathway.