Birt-Hogg-Dubé syndrome is caused by mutations in the FLCN gene. FLCN interacts with mTOR and is expressed in most tissues, however, until recently its role in adipose tissue has been unknown. Earlier this year Yan et al. (2016) showed that loss of FLCN regulates browning of adipose tissue via AMPK. Now, Wada et al. (2016) … Read more…
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