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Chinese Academy of Sciences

A schematic diagram illustrates a proposed mechanism of interferon-γ (IFN-γ)-induced downregulation of tricellulin in salivary epithelial cells. IFN-γ leads to the phosphorylation of signal transducer and activator of transcription 1 (STAT1) and then induces the upregulation of microRNA-145 (miR-145) which combines with tricellulin mRNA 3' UTR and inhibits the expression of tricellulin. This would then cause the dysfunction of acinar epithelial barrier and the increased transports of macromolecules through paracellular pathway due to the loss of tricellulin in salivary glands, thereby resulting in hyposalivation. The schematic diagram is designed by Figdraw.

New Hope for Millions: Researchers Find Key to Treating Painful Dry Mouth Disorder

Categories Health

plastic particles

How Tiny Plastic Particles Are Silently Stealing Food From Your Plate

Categories Earth, Energy & Environment, Social Sciences

Integrating GGO-based Optimization for Solar PV System Performance.

How Greylag Geese Could Help Farmers Harness Solar Power More Efficiently

Categories Earth, Energy & Environment, Life & Non-humans, Technology

Graphic rendition of the 4680 Tesla Cell (silver cell in the picture) and BYD Blade Cell (blue cell in the picture), including cross sections of both cells.

Engineers took apart batteries from Tesla and China’s leading EV manufacturer to see what’s inside

Categories Earth, Energy & Environment, Technology

Gelatin-hydrogel wrapped skin organoids promote wound healing in frostbite-affected skin.

Healing Frostbite Without Scars: The Promise of Skin Organoids

Categories Health, Technology

psticide infographic

Smart Pesticide Changes Color and Self-Destructs After Killing Pests

Categories Earth, Energy & Environment

green tea

Scientists Uncover Gene Behind Caffeine Production in Tea Plants

Categories Health

Solar farm in desert

New Research Field Studies How Solar Farms Affect Desert Life

Categories Earth, Energy & Environment

Schematic of DIW for printing bioceramics. a Printing process of scaffolds either by extrusion screw or compressed air methods; b Scaffolds’ design according to different rectilinear or honeycomb infilling patterns layer-by-layer, top view and cross-section of scaffolds after printing; c Post-processing methods for bioceramic scaffolds after printing. Created using Biorender.com

3D-Printed Bone Grafts Herald New Era in Facial Reconstruction

Categories Health, Technology

Diabetes Linked To Bacteria Invading The Colon, Institute For Biomedical Sciences Study Finds

Natural Compound Shows Promise in Protecting Against Inflammatory Bowel Disease

Categories Health

The proposed vortex beam can carry vast amounts of information, making them ideal for dense data communication systems.

Novel Light-Bending Technology Could Transform Data Security and Transmission

Categories Physics & Mathematics, Technology

Baltimore, Maryland's Mount Vernon neighborhood.

Scientists Discover How to Calculate Citywide Cooling Effects of Urban Trees

Categories Earth, Energy & Environment

Top 20 AI systems in terms of carbon emission for a single training run.

AI’s Hidden Environmental Cost: China Study Reveals Massive Carbon Footprint

Categories Earth, Energy & Environment, Social Sciences, Technology

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