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Cincinnati Children's Hospital Medical Center

Leukemia Cells

Gut Bacteria Metabolite Found to Drive Pre-Leukemic Cell Growth

Categories Health

CARD14 directly binds and regulates MYC, a protein involved in controlling cell growth that can contribute to cancer when it malfunctions. A study published in Cell Reports shows that the proper interaction between these two proteins is important for a healthy skin barrier.

New Skin Barrier Mechanism Uncovered, Offering Hope for Eczema and Psoriasis Treatments

Categories Health

Inhibition of an ESI1 target promotes oligodendrocyte myelin production in mice, as shown as a dense curtain of green strands. This small molecule shows early promise as a potential treatment for MS, and to manage aging-related nerve sheath deterioration, according to study led by experts at Cincinnati Children's.

Breakthrough Treatment Reverses Myelin Damage in Multiple Sclerosis, Study Finds

Categories Brain & Behavior, Health

Control mice show the ability to clear away an experimental infection (images in the left column). But mice with impaired antimicrobial programs show increased intestine damage and inflammation (images in the right column), according to a study published in the Journal of Experimental Medicine.

Study to decode microbe-gut signaling suggests potential new treatment for IBD

Categories Health

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