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UC Irvine

Founded in 1965, UCI is a top-ranked university dedicated to research, scholarship and community service. Led by Chancellor Michael Drake since 2005, UCI is among the most dynamic campuses in the University of California system, with more than 28,000 undergraduate and graduate students, 1,100 faculty and 9,400 staff. Orange County’s second-largest employer, UCI contributes an annual economic impact of $4.3 billion. For more UCI news, visit news.uci.edu.
The study examined the brains of two types of mice: normal mice and mice with Alzheimer's disease. The mice were exposed to purified air or very small particles in the air. The researchers wanted to see if there were any changes in a type of brain cell called astrocytes. The astrocytes were stained green in the images, and the harmful and activated astrocytes appeared red. The merged images showed that the harmful astrocytes were more prevalent in the brains of the Alzheimer's mice exposed to the small particles. This suggests that exposure to these particles can activate harmful astrocytes in the brains of mice with Alzheimer's disease.

Traffic pollution weakens brain function

UC Irvine
Categories Brain & Behavior, Earth, Energy & Environment
“The gene silencing Dz 46 enzyme we developed through chemical engineering has the ability to distinguish and cut a single point mutation in an RNA strand,” says John Chaput, UCI professor of pharmaceutical sciences and corresponding author. “When you are talking about precision medicine for patients, it doesn’t get more precise than that.” Steve Zylius / UCI

Gene silencing DNA enzyme can target single molecule

UC Irvine
Categories Health, Technology
Sergey Nizkorodov, UCI professor of Chemistry (left), and atmospheric chemist Christian George of the National Center for Scientific Research at the University of Lyon, France, led a project to derive a new understanding of how hydroxide molecules help clear the atmosphere of human-emitted pollutants and greenhouse gases. UCI

Scientists discover a way Earth’s atmosphere cleans itself

UC Irvine
Categories Earth, Energy & Environment
Illustration of human brain

How our brains turn into smarter disease fighters

UC Irvine
Categories Brain & Behavior, Health
Ocean

Global warming may shutdown ocean deep circulation

UC Irvine
Categories Earth, Energy & Environment

Stone-eating microbes could help humans colonize the moon and Mars

UC Irvine
Categories Life & Non-humans, Space
Two subadult in proximity. They share a strong friendship bond.

COVID-19 Virus Infects Neurons, Induces Inflammation in the Brains of Monkeys

UC Irvine
Categories Brain & Behavior, Health
Woman in pickup truck

Greener trucking would benefit disadvantaged Californians more than greener buildings

UC Irvine
Categories Earth, Energy & Environment, Social Sciences

Eye-opening discovery about adult brain’s ability to recover vision

UC Irvine
Categories Brain & Behavior, Health

Circadian rhythm disruption found to be common among mental health disorders

UC Irvine
Categories Brain & Behavior, Health
Rich man born poor

Rich people from humble origins are less sensitive to the challenges of poverty than those born rich, research finds

UC Irvine
Categories Brain & Behavior, Social Sciences
blood in a test tube

Researchers find possible blood biomarker for suicide

UC Irvine
Categories Brain & Behavior, Health
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