California Physicians Dropping Out of Managed Care

Only 58 percent of patient care physicians in California are accepting new patients with HMO coverage, and the “California Model” of loose networks of private practice physicians organized into large managed care practice organizations is unraveling, according to University of California research. “California led the nation’s charge into managed care. Our study of the state’s physicians tells us that California has now sounded the retreat,” said Kevin Grumbach, MD, director of the Center for California Health Workforce Studies. “Private physicians are starting to abandon HMOs, IPAs and managed care networks.”

Beer, yeast offer new insight into evolution

Researchers studying yeast reproductive habits have for the first time observed a rapid method for the creation of new species, shedding light on the way organisms evolve. “Most models of speciation require gradual change over a very long period of time, and geographic or ecological isolation for a new species to arise,” says University of Houston biologist Michael Travisano. “Our study suggests that mating two separate species to produce hybrids can result in a new species readily and relatively quickly, at least in yeast, but possibly in other organisms as well.”

North, Central America could face Africa-like AIDS spread

The social behavior of sex workers and transportation workers along the U.S. ? Mexico border has the potential to spread HIV and AIDS through North and Central America in much the same way the disease has spread through sub-Saharan Africa, according to a new University of Houston study. “The main thrust of the study focuses on the potential this social mechanism could play in the spread of AIDS as the virus gets into those populations of truck drivers,” said the study’s lead researcher. “Keep in mind that this is how the virus is believed to have spread throughout sub-Saharan Africa, as transportation workers moved through border regions.”

Grape seed extract may help wound healing

Grape-seed extract may help skin wounds heal faster and with less scarring, a new study suggests. The extract seemed to aid wound healing in two ways: It helped the body make more of a compound used to regenerate damaged blood vessels, and it also increased the amount of free radicals in the wound site. Free radicals help clear potentially pathogenic bacteria from a wound.

Listening to music while working out helps people with severe lung disease

Researchers believe that listening to music helped people with severe respiratory disease increase their fitness levels, based on the results of a new study. Subjects with serious lung disease who listened to music while walking covered an average of 19 total miles over the course of an eight-week exercise intervention study. In comparison, the group that didn’t listen to music only walked an average of 15 total miles ? 21 percent less – by the end of the study. That four-mile difference is significant, said Gerene Bauldoff, a study co-author and an assistant professor of nursing at Ohio State University. It suggests that participants in the music group may have felt less hindered by shortness of breath, the primary physical symptom of serious lung disease.

Caught sleeping: Study captures virus dormant in human cells

Scientists have taken an important step toward understanding a virus that infects and lies dormant in most people, but emerges as a serious illness in transplant patients, some newborns and other people with weakened immune systems. The virus, called human cytomegalovirus, enters the bone marrow and can hide there for a lifetime. Until now, however, scientists had not been able to study the virus in its latent stage because it infects only humans and does not readily infect or become dormant in laboratory strains of bone marrow cells. In a new study researchers demonstrated a laboratory system for studying the virus in its latent stage and discovered a set of genes that may give the virus its great capacity for stealth.

From the bone of a horse, a new idea for aircraft structures

The horse, a classic model of grace and speed on land, is now an unlikely source of inspiration for more efficient flight. So says a group of University of Florida engineers who have recreated part of a unique bone in the horse’s leg with an eye toward lighter, stronger materials for planes and spacecraft.
The third metacarpus bone in the horse’s leg supports much of the force conveyed as the animal moves. One side of the cucumber-sized bone has a pea-sized hole where blood vessels enter the bone. Holes naturally weaken structures, causing them to break more easily than solid structures when pressure is applied. Yet while the third metacarpus does fracture, particularly in racehorses, it doesn’t break near the hole – not even when the bone is subjected to laboratory stress tests. UF engineering researchers think they’ve figured out why – and they’ve built and are testing a plate that mimics the bone’s uncanny strength in a form potentially useful for airplanes and spacecraft.

Researchers question authenticity of new malaria drug

A new investigation by The Scientist magazine reveals that some researchers believe the anti-malaria drug Malarex has not been adequately tested or, worse still, may be a fraud. The drug, touted by its Canadian manufacturer Millenia Hope as safe and effective, is already approved for sale by five African nations. However, respected researchers point to a serious lack of basic research on this drug, which is based on a herbal remedy.

Common human virus may be associated with colon cancer

An association between a common human virus and colon cancer has been established by a group of researchers in the U.S., suggesting a possible role for it in the development of cancer in the human intestinal tract. The so-called JC virus most likely infects humans through the upper respiratory tract and remains in a latent stage in most people throughout their lives, and, in some cases, causes minor sub-clinical problems. But in people whose immune systems are depressed, either through chemotherapy given to organ transplant recipients or an illness such as AIDS, JCV can become active and may contribute to cancer in the brain or cause the fatal demyelinating disease Progressive Multifocal Leukoencephalopathy (PML).

Pot’s distant relative may be next prozac

Man-made chemicals that are distant relatives of marijuana may eventually become new drugs to combat anxiety and depression, according to a California study. The study is the first to show how anxiety is controlled by the body’s anandamide system, a network of natural compounds known for their roles in governing pain, mood and other psychological functions.

Combining key ingredients of vegetarian diet cuts cholesterol

A diet combining a handful of known cholesterol-lowering plant components cut bad cholesterol by close to 30 per cent in a recent study by Candian researchers. The reduction is similar to that achieved by some drug treatments for high cholesterol, suggesting a possible drug-free alternative for combating the condition.

Scientists Find that Ulcer-Causing Pathogen Uses Hydrogen for Energy

In a new study, a microbiologist has discovered that the bacteria associated with almost all human ulcers – one that is also correlated with the development of certain types of gastric cancer in humans – uses hydrogen as an energy source. The finding is novel because most bacteria use sugars and other carbohydrates to grow, says Dr. Jonathan Olson, assistant professor of microbiology at North Carolina State. The human pathogen Helicobacter pylori does not.

Protein in Eye May Help Fight Autoimmune Diseases

A protein found in the eye and involved in its “immune privilege” has prevented and halted autoimmune eye disease in animal models and promises to aid in preventing and treating other autoimmune diseases, including multiple sclerosis and diabetes, according to scientists at the Schepens Eye Research Institute at Harvard University. Immune privilege is a special property of the eye that allows the eye to protect itself without the inflammation caused by the body’s conventional immune response to injury and infection.