Every supplement has its downside. Metformin and rapamycin are the best candidates among fully-developed products, and metformin can dissipate the benefits of exercise, while rapamycin can suppress immune response and raise insulin resistance. NAD enhancers can affect epigenetic methylation and damage the liver. I’ve written about the adverse effects of anti-oxidants, which are the most highly publicized treatments for aging. But glutathione (GSH) is one anti-oxidant for which I’ve read multiple benefits, and I’ve never seen a negative word. As far as I know, the more glutathione you have, the healthier you can expect to be.
Gutathione is akin to
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