Health
Orcas and Elephants--Aging and the Taboo Subject of Population Regulation
One species has come to sit atop the biosphere in much of the world, to dominate and transform the world’s ecosystems.
Aug 13, 2015
Column
Josh Mitteldorf
Aging & evolutionary biology
Josh Mitteldorf is best known for promoting the theory that aging is not “wearing out” but rather an evolved program that limits lifespan. The surprising fact that our bodies are genetically programmed to age and to die offers an enormous opportunity for medical intervention. He began blogging about aging on this site in 2012. His guidance for a long life is at AgingAdvice.org. His two books on aging are available at Amazon and elsewhere.
Mitteldorf’s PhD is in astrophysics. Since about 2020, he has taken up a new challenge as curator and critic of science on the fringe, writing about promising science that the science establishment has unjustly neglected.
In other areas of life, Mitteldorf’s two daughters were among the first girls to be adopted from China in the 1980s. He has taught a weekly yoga class for fifty years. He is an avid amateur musician, playing piano in chamber groups, French horn in community orchestras. Follow his other writing at mitteldorf.substack.com, and listen to his poetry on YouTube.
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Health
The Mystery of Aging, Solved at Last!
How many headlines have you seen that purport to reveal THE secret of aging? Just in the last few weeks, there have been several fundamental, earthshaking, paradigm-shifting, game-changing, disruptive discoveries--and they were very different one from another.
Aug 7, 2015
Health
Funding Policies Distort Science
The more unpredictable the result, the more important the experiment.
Jul 23, 2015
Health
Aging in Microbes
Aging is very old. Long before there were plants and animals, aging was fully-developed in one-celled eukaryotes and before that in bacteria.
Jul 13, 2015
Health
Fasting-Mimicking Diet - A Disclaimer
Last week, I suggested a do-it-yourself version of Dr Longo's FMD diet, and offered sample recipes.
Jul 8, 2015
Health
Can anything be done about Parkinson's Disease?
The main reason I am enthusiastic about Selegiline is because of its potential as a life extension drug.
Jul 6, 2015
Health
One Week, Two Innovations in Aging and Health
Incremental advances in understanding the genetics, epigenetics, and biochemistry of aging are gradually pushing the field forward.
Jun 26, 2015
Health
Correlation and Causation--Nuts and Chocolate
Nuts are a big part of my diet. It’s my habit to eat handfuls of nuts through the day, and a few times a week to incorporate almonds or cashews or peanuts into a main course.
Jun 23, 2015
Health
Dreams of a Pill to Enable Regeneration
Eight years ago, I assumed erroneously that the chute of my food processor was longer than my fingers.
Jun 16, 2015
Health
Is there an Aging Clock in the Hypothalamus?
The brain does its work with electrical signals through a network of neurons. The information is passed to every cell in the body with chemical signals, hormones, RNAs and proteins that are dissolved in the blood.
Jun 12, 2015
Health
Preserving Insulin Sensitivity
The body adjusts its rate of aging in response to environmental cues. Most influential is diet.
Jun 4, 2015
Health
Vital Questions, Part 3
May 26, 2015