Health
Three Technologies to Watch
1. Thymus Regrowth with FOXN1 The thymus gland is a time bomb that would kill us at a certain age, if nothing else got us first.
Nov 24, 2014
Column
Josh Mitteldorf
Aging & evolutionary biology
Josh Mitteldorf is best known for promoting the theory that aging is not “wearing out” but rather an evolved program that limits lifespan. The surprising fact that our bodies are genetically programmed to age and to die offers an enormous opportunity for medical intervention. He began blogging about aging on this site in 2012. His guidance for a long life is at AgingAdvice.org. His two books on aging are available at Amazon and elsewhere.
Mitteldorf’s PhD is in astrophysics. Since about 2020, he has taken up a new challenge as curator and critic of science on the fringe, writing about promising science that the science establishment has unjustly neglected.
In other areas of life, Mitteldorf’s two daughters were among the first girls to be adopted from China in the 1980s. He has taught a weekly yoga class for fifty years. He is an avid amateur musician, playing piano in chamber groups, French horn in community orchestras. Follow his other writing at mitteldorf.substack.com, and listen to his poetry on YouTube.
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Health
Nicotinamide Riboside -- Where’s the Beef?
NR is a supplement that affects energy generation in mitochondria and gene regulation through the same pathway as resveratrol and caloric restriction.
Nov 17, 2014
Health
Quick Notes from Quebec
We scratch our heads, we wonder what went wrong. To clearly programmed death we pay no heed… And comfort find we in familiar song: “Respect the body’s wisdom” is our creed.
Nov 6, 2014
Health
Open Letter on Research Priorities in Aging
Last week, I had the honor of speaking with Cynthia Kenyon, who has been recruited by Google to direct research activities at their new venture into aging medicine, called CALICO, for California Life Co.
Oct 29, 2014
Health
Poking Fun at Longevity Science
“In science one tries to tell people, in such a way as to be understood by everyone, something that no one ever knew before.
Oct 29, 2014
Health
Lithium for Life Extension?
Thanks for Michael Eaves for pointing me to sources for this article.
Oct 13, 2014
Health
Anti-aging Oxymorons and Anti-oxi-morons
The natural foods industry is deep into the anti-aging business, and it’s all based on two lies—one about pesticides and toxins, the other about anti-oxidants.
Oct 6, 2014
Health
The Carrot and the Stick
Sep 29, 2014
Health
Smart molecules, Really smart molecules, and the “B team”
I like to think about chromosomes as Torah scrolls in the Arc of the cell nucleus.
Sep 23, 2014
Health
CRISPR in your Future
Sep 15, 2014
Health
Sleep and Longevity
“Shift work [ref] and chronic jet-lag [ref] reduce mental acuity and increase the risk of a number of medical problems including cancer, digestive diseases…
Sep 8, 2014
Health
Transfusing Youth: the epigenetic aging clock hypothesis is about to be tested
Just this past Spring, Tony Wyss-Coray of Stanford demonstrated that infusions of blood plasma from young mice can make old mice grow new brain tissue.
Sep 2, 2014