New technique cuts risks of gene therapy

Stanford researchers have developed a technique that could cut the risks associated with gene therapy. Traditionally, gene therapy involves sneaking a snippet of genes into a person’s DNA via a virus messenger. But the result is the new sequence gets randomly placed within the patient’s existing genes, sometimes triggering other illnesses, such as leukemia. The new technique eliminates the need for a virus delivery system and places the genes in precise locations.

Code-breaking bugs crack plants’ defenses

Researchers have found that plant-eating insects use a form of molecular code-breaking to protect themselves against repellants employed by their dinner. Scientists in Illinois have detailed how corn earworms (Helicoverpa zea) intercept defensive chemical signals used by their hosts and then produce detoxifying agents to partially counter the threat against them.

Biologist Offers a Solution to the ‘Freeloaders Paradox’

Freeloaders ?? individuals eager to join social groups, but who once in, tend to avoid pulling their fair share of the chores ?? have long posed something of a problem for evolutionary biologists. In theory, because freeloaders don?t expend the efforts and energy of their more civic-minded neighbors, they should be able to translate that energy into more offspring, spreading their “slacker genes” and overrunning the world with offspring of similar ilk. But that doesn’t happen, and an Arizona researcher thinks she knows why.

One to go

Oh Vladimir. We had such high hopes for you. Five years after your countryman lost to Deep Blue, it looked for a while there that you would actually defeat its silicon successor, Deep Fritz. But now, after an initial spurt of victory, Fritz has pulled even, just one game away from condemning humans again to the trash heap of chess playing history. Sure, you sound optimistic. “I’m not depressed,” you say. “When you play such a wonderful game you can’t be. It could have gone either way. Fritz played such great defense. I think I can still win the match.” But with $1 million riding on the outcome of the “Brains in Bahrain” competition, can your nerves handle the pressure?

Thar she blows?

Mauna Loa,? Hawaii’s biggest and potentially most destructive volcano,? is showing signs of life again nearly two decades after its last eruption. Recent geophysical data collected on the surface of the 13,500-foot volcano revealed that Mauna Loa’s summit caldera has begun to swell and stretch at a rate of 2 to 2.5 inches a year, according to scientists from the U.S. Geological Survey and Stanford University. Surface inflation can be a precursor of a volcanic eruption, the scientists warn.

Kids with Down syndrome learn language beyond adolescence

Researchers have traditionally thought that language learning in children with Down syndrome stopped during the teenage years. As a result, Down youth typically received no language instruction after puberty. But a new study suggests the opposite: that individuals with Down syndrome can benefit from language intervention programs during adolescence and beyond, precisely because it takes them longer to learn. Down syndrome is a developmental disability resulting from an extra copy of chromosome 21, and it affects about 5,000 newborns in the United States every year. Most children begin learning language skills, such as grammar and speaking, at rapid rates early in their lives. Children with Down syndrome, however, typically experience delays in language development, learning more slowly and at varying rates.

Valium-like drug helps treat lupus

A cousin to the anti-anxiety drug Valium has been shown in mice to reduce some of the symptoms associated with lupus. Lupus is an autoimmune condition in which the immune system attacks the body’s own tissues. “The best available therapies for lupus haven’t changed for many, many years,” says U-M’s Gary D. Glick, Ph.D., one of the lead authors on the study. “It’s a disease where the mechanisms that normally prevent the immune system from attacking components of one’s own body are defective. Because we do not yet understand what triggers lupus, it has been very difficult to develop lupus-specific therapies.”

Now for something really important … pork!

Treating pork and other livestock meat with plain old baking soda improves the taste, Wisconsin researchers have found. “For years consumers have noticed that pork quality is inconsistent. A major reason is that the meat from some pigs becomes pale, soft and watery after they are slaughtered, according to Robert Kauffman, an expert on pork quality and a UW-Madison emeritus professor.” Vegetarians in the audience should move on now, as this clearly meat-friendly story may make you a little uncomfortable.

Researchers to test smallpox vaccine

Researchers in Northern California are conducting a clinical trial that will test whether diluted doses of the smallpox vaccine produce adequate immunity in adults who have previously been vaccinated. The results of the federally funded study, for which volunteers are now being sought, will help shape U.S. policy on how the vaccine would be given in the event of a smallpox outbreak.

See also:
When rashes kill
Facing disfigurement in 2002
Smallpox immunity lasts longer than thought

Vet develops cheap manatee chow for injured animals

Fifty pounds of romaine lettuce makes enough Caesar salad for a hundred people, but it?s just a one-day food supply for a manatee in captivity. To feed the endangered aquatic mammals more economically while they recover from injuries or medical treatment, a University of Florida veterinarian has developed a new manatee chow that costs one-tenth the price of lettuce. The discovery comes at a time when manatee injuries and subsequent deaths have reached record rates. In 1986, 122 manatees died in Florida. Fifteen years later, that number climbed to 325.

Strange attraction: Shaping metal with magnets

Researchers in Ohio say they’ve come up with a way to shape metal using powerful magnetic fields, a process that could help cut down on the use of toxic lubricants otherwise needed to stamp products as diverse as auto parts and kitchenware. Said one of the researchers: “The process has to be reliable, and require as little human intervention as possible…. In automobile production especially, manufactures need to make parts in as few steps as they possibly can. I think we can do a lot of good things for industry with this technique.”

Coenzyme Q10 slows Parkinson’s in study

High doses of the naturally occurring compound coenzyme Q10 has been found to slow by 44 percent the deterioration in function that occurs in Parkinson’s disease. The greatest benefit was seen in everyday activities like eating, dressing, bathing and walking. But researchers say that before people run out to RightAid for a barrel of the stuff, a wider study is needed (this one tracked 80 patients). Parkinson?s is a degenerative disorder of the brain in which patients develop tremor, slowness of movement and stiffness of muscles. It affects about 1 percent of Americans over the age of 65.

See also: Parkinson’s patients look to gene therapy