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Autophagy

The mechanism of astrocytic autophagy plasticity plays a crucial role in AD. When the autophagy-regulating genes (LC3B and SQSTM1) in astrocytes are activated, Aβ is efficiently removed, which is important for cognitive recovery.

New brain cell cleaner: astrocytes raise possibility of Alzheimer’s disease treatment

Categories Brain & Behavior

When the protein STING (pink) is activated, the transcription factor TFEB (green) is shuttled into the nucleus where it stimulates the production of lysosomes

STING Protein Plays Dual Role in Cellular Health and Aging, Pitt Study Finds

Categories Health

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