PHILADELPHIA — Reporting in Nature, scientists from Thomas Jefferson University have determined that a single protein called FADD controls multiple cell death pathways, a discovery that could lead to better, more targeted autoimmune disease and can…
When it comes to health care blue lights, are usually most useful on the top of ambulances but now new research led by the University of Warwick has found a way to use blue light to activate what could be a highly potent platinum-based cancer treatm…
Drug resistance is a major obstacle in curing ovarian cancer but new research from the Centenary Institute has discovered a treatment that kills ovarian cancer cells in a new way that can break the resistance mechanism. Published today in Autophagy…
The best cancer drugs in the world are not much good if they cannot get to tumor cells. That problem has been challenging cancer physicians and researchers for years because the physical structure of many tumors can prevent anticancer agents from reaching their targets. In a study appearing in the June issue of Nature Medicine, researchers from Massachusetts General Hospital (MGH) describe a new technique for assessing the permeability of tumors and a promising new way of improving tumors’ accessibility to drugs.
Cancer patients undergoing chemotherapy often endure painful side effects caused by the powerful drugs as they course through their entire bodies, damaging healthy tissue and tumors alike. Utah researchers are reporting in the December issue “Cancer Research” that they have successfully tested a new method in laboratory animals that would concentrate the impact of cancer drugs on specific cancerous tissues, thus sparing the rest of the body from harm.
Today, even the best cancer treatments kill about as many healthy cells as they do cancer cells. But a St. Louis researcher has begun to lay the conceptual and experimental groundwork for a new strategy for chemotherapy — one that turns existing drugs into medicinal “smart bombs.” The approach is essentially a sophisticated drug releasing system, one that can recognize and use cancerous DNA sequences as triggering mechanisms for the drugs that fight them.