Essential gene for male fertility found

A gene that belongs to a family of genes implicated in heart disease has been found to be essential for male fertility but has no impact on female fertility, researchers at U of T, along with colleagues in New York and Japan, have discovered.

Semen quality may start to decline in one's 20s

With each passing year, semen quality in adult men declines, suggesting that age plays a greater role in male fertility rates than previously thought, according to a new study by researchers at the University of California, Berkeley, and Lawrence Livermore National Laboratory. The study, published Thursday, Feb. 6, in the journal Human Reproduction, suggests that even healthy men may become progressively less fertile as time goes by.

Mice in the news

It has been a big week for the common lab mouse. Tests in mice showed that the deadly botulism toxin could be neutralized with an experimental drug. The drug, fashioned from two antibodies from mice and one from a human, could be mass-produced and thus could be used as a deterrent to the use of botulism toxin as a weapon. In other mouse news, scientists at the Universiy of Pennsylania have figured out that they can turn mice into goat and pig sperm “factories” by grafting testes onto their backs. The technique could be used in the future to make sperm for young cancer patients left infertile after treatment, to help human couples struggling with male fertility problems, and to preserve species close to extinction. The most amazing mouse news of the week? Researchers at the Dana-Farber Cancer Institute in Boston created a transgenic mouse with Lance Armstrong-like capabilities, able to endure hard exercise for extended periods of time.