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neuroscience

Mutations in the presenilin gene, PSEN1, causes early onset of Alzheimer’s disease in humans and in fruit flies modified to have this gene. A new study led by researchers at Penn State revels that disrupting heparan sulfate–modified proteins in fruit flies suppressed neuronal death and corrected other cell deficits common in early stages of Alzheimer’s and other neurodegenerative diseases. Pictured here are full fruit fly brains, stained with a marker that indicates cell death—brighter colors indicate higher presence of cell death. Top: A fly with deficits in the presenilin gene—a model for Alzheimer’s disease—with high levels of cell death. Bottom: A fly rescued by disrupting heparan sulfate–modified proteins.

Potential new target for early treatment of Alzheimer’s disease

Categories Brain & Behavior

A cross-section of the somatosensory cortex in a young mouse brain. A key receptor protein named mGluR1 (green) is necessary to prime sensory circuits early in life, affecting how the mouse senses the world through touch.

Brain Protein Discovery Could Lead to New Autism Treatments

Categories Brain & Behavior

Brain, magnifying glass illustration

Amnesia caused by sleep deprivation could be reversed with existing drugs

Categories Brain & Behavior

Lab mouse.

CBD Use During Pregnancy May Alter Offspring Behavior and Brain, Mouse Studies Suggest

Categories Brain & Behavior, Life & Non-humans

Researcher Christine Skjegstad

Brain Responds Differently to Human and AI Voices, Despite Difficulty Distinguishing Them

Categories Brain & Behavior, Technology

Bacteria in the gut convert bile acids produced by the liver into a wide array of new compounds. These molecules are akin to the language of the gut microbiome, allowing them to influence distant organ systems. Photo Credit: Lakshmiraman Oza/Pixabay

Resilient People Show Unique Brain and Gut Microbiome Patterns

Categories Brain & Behavior, Health

The PtNGrid features thin, flexible and densely packed grids of either 1,024 or 2,048 embedded electrocorticography (ECoG) sensors.

FDA Approves Clinical Trial for High-Resolution Brain Recorder

Categories Brain & Behavior, Health, Technology

Individual emotions take turns guiding Inside Out 2’s main character, Riley, but new research finds that if Riley were to have mixed emotions, the scene might be animated a bit differently. (Image: Courtesy of Disney.)

Are mixed emotions real? New research says yes

Categories Brain & Behavior

warhol-style-illustration-of-two-brains-face-to-face.-The-left-half-has-a-red-background-and-blue-brain.-The-right-half-has-a-blue-background

Neural balance in the brain is associated with brain maturity and better cognitive ability

Categories Brain & Behavior

Togetherness concept. People hands throwing coins in piggy bank for crowdfunding, white background

What is the neural mechanism behind helping someone at your own cost?

Categories Brain & Behavior

In this image adapted from the figures, the left side shows the chip micrograph, while the right side displays the pixel layout and schematics, highlighting each circuit element. The new pixel circuit uses only two additional transistors (T5 and T6) compared to the conventional CMOS pixel. This minimalist design allows for independent programming of pixel exposures without sacrificing photodiode area to the circuits, ensuring high sensitivity under low light conditions.

MIT Researchers Unveil Innovative Image Sensor for Enhancing Neural Activity Visualization

Categories Brain & Behavior, Technology

Brain illustration

Scientists Unravel the Neural Mechanisms of Planning

Categories Brain & Behavior

Confused Woman Searching For Food In An Open Refrigerator

New home-administered treatment for binge eating disorder shows promising results

Categories Brain & Behavior, Health

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