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Cold Spring Harbor Laboratory

Cold Spring Harbor Laboratory’s Furukawa lab is studying an autoimmune disease called anti-NMDAR encephalitis in collaboration with Professor Christian Geis’ team at the University of Jena and the SYNABS research unit in Germany. Here, we see antibodies from a human anti-NMDAR encephalitis patient (purple) binding to NMDARs (green) in a mouse brain. Areas marked red indicate high levels of antibody binding. Additionally, the impact of these antibodies on memory could be assessed using a new system established in collaboration between Furukawa and colleagues at the Max Planck Florida Institute for Neuroscience.

New Research Sheds Light on Anti-NMDAR Encephalitis, Offering Hope for Personalized Treatments

Categories Brain & Behavior, Health

A cross-section of the somatosensory cortex in a young mouse brain. A key receptor protein named mGluR1 (green) is necessary to prime sensory circuits early in life, affecting how the mouse senses the world through touch.

Brain Protein Discovery Could Lead to New Autism Treatments

Categories Brain & Behavior

a red illustration of chemical bonds

New Click Chemistry Accelerates Drug Discovery, Offers Hope for Cancer, Antibiotic-Resistant Bacteria

Categories Physics & Mathematics, Technology

RNS strands

Cracking the Code: New Insights into RNA Splicing Drugs

Categories Health

For a recent CSHL Cancer Center study, Adjunct Professor Mikala Egeblad (now a Bloomberg Distinguished Professor with Johns Hopkins University) and postdoc Xue-Yan He (now Assistant Professor of Cell Biology & Physiology at Washington University School of Medicine in St. Louis) teamed with CSHL Professor Linda Van Aelst. Above: lung cancer metastasis in a mouse that underwent experiments designed to simulate the stress that cancer patients experience.

Chronic stress spreads cancer. Here’s how

Categories Health

mouse

How a mouse’s brain bends time

Categories Brain & Behavior, Life & Non-humans

Right now, a simple DNA swab can tell you where you came from and which diseases you stand to inherit. In the future, it might give you the means to beat them too.

New software uncovering the link between ancestry and cancer

Categories Health, Technology

Mammalian motivation circuits: Maybe they’re born with it

Categories Brain & Behavior, Life & Non-humans

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