The first draft of the horse genome sequence has been deposited in public databases and is freely available for use by biomedical and veterinary researchers around the globe, leaders of the international Horse Genome Sequencing Project announced today.
A study published in this week’s issue of the New England Journal of Medicine suggests that repeated topical use of products containing lavender oil and/or tea tree oil may cause prepubertal gynecomastia, a rare condition resulting in enlarged breast tissue in boys prior to puberty, and for which a cause is seldom identified.
Researchers have begun a clinical study of oral insulin to prevent or delay type 1 diabetes in at-risk people, the National Institutes of Health (NIH) announced today. Type 1 Diabetes TrialNet, an NIH-funded network of researchers dedicated to the understanding, prevention, and early treatment of type 1 diabetes, is conducting the study in more than 100 medical centers across the United States, Canada, Europe, and Australia.
Variations in a gene known as SORL1 may be a factor in the development of late onset Alzheimer’s disease, an international team of researchers has discovered. The researchers suggest that faulty versions of the SORL1 gene contribute to formation of amyloid plaques, a hallmark sign of Alzheimer’s in the brains of people with the disease.
Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), part of the National Institutes of Health in Bethesda, Md., and colleagues at the University of Virginia in Charlottesville have succeeded in imaging, in unprecedented detail, the virus that causes influenza.
A new imaging molecule that can detect and map plaques and tangles in the brains of people with Alzheimer’s disease could eventually lead to earlier diagnosis of the devastating disease, researchers at the University of California, Los Angeles report in the Dec. 21, 2006, issue of the New England Journal of Medicine. The compound, developed by UCLA and called FDDNP, also holds promise as a research tool to evaluate new treatments for Alzheimer’s.
Scientists from the University of Colorado at Boulder and the Centers for Disease Control and Prevention (CDC) have developed a microchip-based test that may allow more labs to diagnose influenza infections and learn more about the viruses causing illness. The FluChip successfully distinguished among 72 influenza strains—including the H5N1 avian influenza strain—in less than 12 hours. The research was led by University of Colorado scientist Kathy L. Rowlen, Ph.D., and was funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). It appears in the current issue of the Journal of Clinical Microbiology.
Overweight aged male mice whose high calorie (fat) diet was supplemented by resveratrol, a natural compound found in common foods like grapes, wines and nuts, had better health and survival than aged overweight mice who did not receive it, according to a study published online in the Nov. 1 issue of Nature. The study was conducted and supported in part by the National Institute on Aging (NIA) of the National Institutes of Health (NIH).
A research center newly created by the University of California, Berkeley, and Lawrence Berkeley National Laboratory (LBNL) aims to put light-sensitive switches in the body’s cells that can be flipped on and off as easily as a remote control operates a TV. Optical switches like these could trigger a chemical reaction, initiate a muscle contraction, activate a drug or stimulate a nerve cell – all at the flash of a light.
The National Institutes of Health (NIH) announces a nationwide study to see if a modified combination of vitamins, minerals, and fish oil can further slow the progression of vision loss from AMD, the leading cause of vision loss in the United States for people over age 60. This new study, called the Age-Related Eye Disease Study 2 (AREDS2), will build upon results from the earlier Age-Related Eye Disease Study (AREDS). The original study results were released five years ago today. The study found that high-dose antioxidant vitamins and minerals (vitamins C and E, beta-carotene, zinc, and copper), taken by mouth, reduced the risk of progression to advanced AMD by 25 percent, and the risk of moderate vision loss by 19 percent.
Scientists have identified a misfolded, or incorrectly formed, protein common to two devastating neurological diseases, frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig’s disease), according to a report in the Oct. 6, 2006, issue of Science. The findings suggest that certain forms of FTD, ALS and possibly other neurological diseases might share a common pathological process.
Relapse to uncontrolled drinking after periods of sobriety is a defining characteristic of alcoholism and is often triggered by stress. A new study in rats reports that a specific receptor for a stress-response transmitter may play an important role in stress-induced relapse.
If you’ve had a heart attack or stroke, paramedics, doctors, and nurses follow standardized protocols for what to do right away, and their efforts improve your odds for a full recovery. That’s not the case if you have a body-wide infection known as sepsis, which can be fatal within a few hours and is often not diagnosed until it is too late.
The National Institute of Mental Health, part of the National Institutes of Health, has launched three major clinical studies on autism at its research program on the NIH campus in Bethesda, Maryland. These studies are the first products of a new, integrated focus on autism generated in response to reported increases in autism prevalence and valid opportunities for progress. Initial studies will define the characteristics of different subtypes of autism spectrum disorders and explore possible new treatments.