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Washington University in St. Louis

A brain scan of a neurofibromatosis type 1 (NF1) patient reveals a tumor on the optic nerve connecting the left eye to the brain (right side of the image). Researchers at Washington University School of Medicine in St. Louis have discovered that an FDA-approved epilepsy drug can prevent or slow the growth of NF1-linked optic gliomas in mice, laying the groundwork for a clinical trial.

Epilepsy drug prevents brain tumors in mice with NF1

Categories Health

Scientists at Washington University School of Medicine in St. Louis have shown that treating mice with an antibody that blocks the interaction between APOE proteins (white) sprinkled within Alzheimer’s disease plaques and the LILRB4 receptor on microglia cells (purple) activates them to clean up damaging plaques (blue) in the brain.

New Alzheimer’s Treatment Shows Promise by Activating Brain’s Immune Cells

Categories Brain & Behavior, Health

infant

Five factors to ensure an infant thrives

Categories Brain & Behavior, Health, Social Sciences

Mice illustration

Life span increases in mice when specific brain cells are activated

Categories Health, Life & Non-humans

Man smoking. Unsplash

Smoking causes brain shrinkage

Categories Brain & Behavior, Health

DNA illustration

Clues to preventing Alzheimer’s come from patient who, despite genetics, evaded disease

Categories Brain & Behavior

Lipid deposits (green) in brain immune cells (red) from mice with Alzheimer’s-like disease all but disappear (right) after the mice are treated with an experimental drug. Researchers at Washington University School of Medicine in St. Louis have found that a form of cholesterol known as cholesteryl esters builds up in the brains of mice with Alzheimer’s-like disease, and that clearing out the cholesteryl esters helps prevent brain damage and behavioral changes.

Lowering a form of brain cholesterol cuts Alzheimer’s-like damage in mice

Categories Brain & Behavior

Shrimp

Fiber from crustaceans, insects, mushrooms promotes digestion

Categories Health

Snowy woods.Pixabay

Blowing snow contributes to Arctic warming

Categories Earth, Energy & Environment, Physics & Mathematics

Kanta Horie, PhD, works with a mass spectrometer that he uses to measure protein levels in cerebrospinal fluid samples. Horie and colleagues at Washington University School of Medicine in St. Louis and Lund University in Sweden have discovered that a form of the protein tau in the cerebrospinal fluid known as MTBR-tau243 can be used to track the progression of Alzheimer's disease and could speed drug development.

Tau-based biomarker tracks Alzheimer’s progression

Categories Brain & Behavior, Health

A team of researchers at the McKelvey School of Engineering and the School of Medicine has developed a proof-of-concept air quality monitor that can detect live SARS-CoV-2 virus in indoor environments. The monitor uses a biosensor made with nanobodies that is integrated into an air sampler that operates based on the wet cyclone technology.

Real-Time Virus Detection: A Breakthrough in Indoor Surveillance

Categories Health, Technology

Treatment-resistant prostate cancer

Treatment-resistant prostate cancer provides its own hormonal fuel

Categories Health

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