Calorie listings don’t encourage overeating, study says

You really don't want to knowLabeling foods “low-fat” is suspected of encouraging consumers to overeat. If that box of Ho-Ho’s claims to be low-fat, heck, why not down the full dozen? But a study from Penn State says the same is not true of the listing of caloric content. “Some studies have shown that people take larger portions of foods labeled ‘low fat’ ? using the label as a license to eat more. This study shows that energy density labels are unlikely to undermine the benefits of offering foods with fewer calories per ounce.”

New prion test faster, more accurate

Researchers say they’ve developed a new test for prions that improves the accuracy and speed with which the malformed and infectious proteins can be detected. Prions cause neurodegenerative diseases in sheep, deer and elk, plus Mad Cow disease in cattle and Creutzfeldt-Jakob in humans.

Who’s the man? Alan Boyle, that’s who!

A big halloo and thanks to MSNBC’s Alan Boyle, who has graciously linked to Science Blog from his terrific Cosmic Log. Boyle’s stuff has been a regular read of mine for a while. And it should be for you too! Incidentally, since we’ve never met Alan, a quick Google image search on his name revealed this intriguing photo. Not only a great writer, but a Mr. Universe candidate as well? (In fact, the real Alan Boyle can be found here :->)

Mutation Causes Huntington’s Symptoms

Researchers have discovered a gene mutation that causes a condition apparently identical to Huntington’s Disease, helping explain why some people with the disorder do not have a separate mutation found in most cases. The finding may help reveal why some diseases, like Huntington’s, Alzheimer’s and Parkinson’s, destroy some brain cells while sparing others. “For all practical purposes this is Huntington’s Disease, yet it’s caused by a different mutation on a completely different chromosome,” said Russell L. Margolis, M.D., associate professor of Psychiatry at Hopkins and director of the Johns Hopkins Laboratory of Genetic Neurobiology. “This is a rare version of an already rare disorder, but the mutation that causes it may not only help us better understand Huntington’s Disease, but could boost our understanding of many other neurodegenerative disorders.”

Cell keeps spare set of DNA to ensure offspring gets fresh start

This is a little complex, but bear with us. Nearly all cells house their DNA inside a nucleus. But a little one-celled critter called Tetrahymena houses different versions of its DNA in each of its two nuclei. Researchers have found that the smaller nucleus (called the micronucleus) just keeps the cell’s full genome safe, acting as a sort of “lock box.” The larger nucleus (called the macronucleus) uses the DNA to regulate the cell’s life functions. When the cell mates to create a new generation, the two work together to compare the cell’s current DNA against what’s been stored in the lock box. If any foreign genes have snuck in (like from a virus) they nuclei eliminate it, to make sure baby gets a fresh start. Pretty neat, with possible implications for larger organisms, too.

Time to adjust the compass?

Working high in the Canadian Arctic, researchers from the University of Rochester say they’ve found that several aspects of the powerhouse that drives the Earth’s magnetic field may be related. That’s new in itself. But the team also thinks it may indicate our planet’s about ready for a pole reversal, in which all compasses will begin pointing south.

Neural stem cells used to hunt, kill brain cancer

Using neural stem cells to hunt down and kill cancer cells, researchers have successfully tested a new treatment for brain cancer. They now hope the technique will lead to an effective treatment for glioma, the most aggressive form of primary brain tumor in humans. As the Cedars-Sianai researchers note, the prognosis has historically been extremely poor for patients diagnosed with malignant gliomas. The tumors have poorly defined margins, and glioma cells often spread deep into healthy brain tissue making their surgical removal difficult. Often, pockets of tumor cells break off from the main tumor and migrate deep into non-tumorous areas of the brain. Therefore, even if the original tumor is completely removed or destroyed, the risk of recurrence is high as cells in these distant “satellites” multiply and eventually re-form a new brain tumor. Due to these characteristics, treating brain cancer has been extremely difficult.

Treating precancerous breast cells can prevent development of cancer

Treating precancerous breast cells with chemopreventive agents like tamoxifen limits the development of breast cancer in genetically predisposed women, according to a new study. Precancerous breast cells may also provide an effective mechanism for screening new and current chemopreventive agents, the study found.

Kilimanjaro ice reveals devastating history, future

Researchers analyzing ice cores taken from Tanzania’s Mount Kilimanjaro say they’ve found evidence of several catastrophic droughts that plagued the tropic over the millennia, and strong signs the ice field itself will disappear within 20 years, the victim of global warming.

Misfolding key to prion’s ability to kill brain cells

Researchers may have discovered the mechanism behind how prions ? pieces of protein molecules? can kill nerve cells in the brain and lead to some serious degenerative diseases. The key seems to lie in how one particular protein misfolds within an organelle inside the cell, transforming itself into a new agent and then poisoning the neuron in which it was made.

Speeding star indicates mondo black hole in middle of Milky Way

Researchers say they’ve successfully tracked a star racing around a dark mass at the center of our Milky Way galaxy, offering strong support for the theory that a black hole is at the center of our little corner of space. Astronomers at the Max Planck Institute for Astrophysics tracked the orbit of the closest known star to the black hole candidate Sagittarius A*, a dark mass 3,000,000 times the mass of the sun. Following the star for 10 years, they found that it does indeed orbit Sagittarius A*. Approaching the black hole’s maw, the star reaches its highest velocity, whizzing past it at 5,000 kilometers per second.

Test could reduce need for biopsies in prostate disease

Men who test positive for elevated prostate specific antigen (PSA) levels sometimes freak out because they think it means they have cancer. To find out, a surgeon will often perform a biopsy. But researchers from the National Cancer Institute and the Food and Drug Administration report that a new test using a single drop of blood could help distinguish between prostate cancer and benign conditions. The trick is identifying patterns of proteins found in patients’ blood serum.

New technique cuts risks of gene therapy

Stanford researchers have developed a technique that could cut the risks associated with gene therapy. Traditionally, gene therapy involves sneaking a snippet of genes into a person’s DNA via a virus messenger. But the result is the new sequence gets randomly placed within the patient’s existing genes, sometimes triggering other illnesses, such as leukemia. The new technique eliminates the need for a virus delivery system and places the genes in precise locations.

Code-breaking bugs crack plants’ defenses

Researchers have found that plant-eating insects use a form of molecular code-breaking to protect themselves against repellants employed by their dinner. Scientists in Illinois have detailed how corn earworms (Helicoverpa zea) intercept defensive chemical signals used by their hosts and then produce detoxifying agents to partially counter the threat against them.