Smart heat pipe efficiently cools laptops, permitting greater speed

Evacuating heat is one of the great problems facing engineers as they design faster laptops by downsizing circuit sizes and stacking chips one above the other. The heat from more circuits and chips increase the likelihood of circuit failures as well as overly heated laps. “Space, military, and consumer applications, are all bumping up against a thermal barrier,” says Sandia researcher Mike Rightley, whose newly patented “smart” heat pipe seems to solve the problem. The simple, self-powered mechanism transfers heat to the side edge of the computer, where air fins or a tiny fan can dissipate the unwanted energy into air.

Full-body CT Scans May Benefit Only Select Group

A full-body computed tomography (CT) scan may be beneficial to fewer people than previously thought, according to a study presented December 3, 2002 at the 88th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA) in Chicago. The results of a second study pointed out the need to establish guidelines and standardized reporting systems for this hotly debated diagnostic procedure.

Hubble helps measure massive extrasolar planet

NASA Hubble Space Telescope’s crisp view has allowed an international team of astronomers to apply a previously unproven technique (astrometry) for making a precise measurement of the mass of a planet outside our solar system. The Hubble results place the planet at 1.89 to 2.4 times the mass of Jupiter, our solar system’s largest world. Previous estimates, about which there are some uncertainties, place the planet’s mass between 1.9 and 100 times that of Jupiter.

Recent products awarded ADA Seal of Acceptance

Just in time for the holidays, the American Dental Association — arbiter of quality in all things related to tooth care — has issued its latest list of ADA-approved goodies. Among the highlights: Saliva Substitute from Roxane Laboratories; Pharmacia Corp.’ s Gelfoam Dental Sponge; Shaw’s Hi-Tech Waxed Floss; lots and lots of powder-free latex gloves; and something called a Basic Continental Doctors Unit, from the considerate folks at A-dec, Inc.

Patient Safety Study Documents Medication Errors in Hospitals

According to a new national report issued today by the United States Pharmacopeia (USP)’s Center for the Advancement of Patient Safety (CAPS), administering drugs using incorrect techniques continues to be a serious cause of injury to hospital patients, increasing costs to insurers. The study collected reported medication errors voluntarily provided by 368 health care facilities nationwide, including community, government, and teaching institutions. Of the 105,603 errors documented, the vast majority were corrected before causing harm to the patient. But 2.4 percent of the total errors were more serious, resulting in patient injury, prolonged hospitalization and even death.

Human, mouse genomes show more genomic rearrangements than expected

An expert in computational biology at the University of California, San Diego (UCSD) estimates that it took many more evolutionary genome rearrangements than previously thought — both large and small — to account for differences in the human and mouse genomes. The findings are included in two landmark papers announced today.

Addicts’ Brains Work Harder to Control Behavior

A brain-imaging study conducted at the U.S. Department of Energy’s Brookhaven National Laboratory reveals that recently abstinent methamphetamine abusers who reported they avoided harmful situations had higher resting metabolic rates in a part of the brain responsible for making decisions and modifying behaviors than those with low harm-avoidance scores. In non-addicted, comparison subjects, there was no significant association between harm avoidance and metabolism in this brain region. The findings, reported in the December 3, 2002, issue of NeuroReport, suggest that this higher-level brain center — the orbitofrontal cortex — is involved in drug addiction, and might be working extra hard in addicts trying to stay off drugs.

Dark Edge of Sunspots Reveal Magnetic Melee

In what may be one of the most important steps in understanding sunspots since they were discovered by Chinese sky watchers more than two millennia ago, researchers have discovered that the lines of magnetic force that surge out of sunspots appear to peel apart like husk off an ear of corn as some of the lines are dragged back beneath the surface by a sort of solar quicksand. This “quicksand” and the magnetic fields it bends create the penumbrae around some sunspots, the strange rings of mid-darkness that have eluded explanation by astronomers since Galileo first sketched them. With the help of sophisticated computer models and data from solar telescopes that give spectacular views of the sun, researchers at the University of Rochester, University of Colorado, University of Cambridge, and University of Leeds have reported an answer to several mysteries of sunspots in the current issue of Nature.

Diabetic gene linked to heart disease

Heart disease is the most frequent, costly and severe complication of diabetes, affecting more than 70 percent of diabetic patients. There are geographic and ethnic differences in the risk of diabetic heart disease that cannot be fully explained by differences in conventional heart disease risk factors. Using a simple blood test, researchers at the Technion-Israel Institute of Technology have identified a gene that determines which diabetes patients are at greater risk for developing heart disease. Unlike other recent breakthroughs, such as the test for C-reactive protein, the test for this gene needs to be administered only once in a patient’s lifetime.

Novel Method for Assembly of Nanoparticles

New York engineers have developed a novel method for assembling nanoparticles into three-dimensional structures that one day may be used to produce new nanoscale tools and machines. The work could be an important step in fulfilling the immense potential of nanotechnology because it gives scientists and engineers improved control and flexibility in the creation of materials for the manufacture of many nanoscale devices. The researchers used non-uniform AC electric fields generated by microfabricated electrodes — which create a motion known as dielectrophoresis — to stack latex, silica or graphite microparticles into two- and three-dimensional structures of prescribed lengths and composition, held together by the electrical field.

From the bone of a horse, a new idea for aircraft structures

The horse, a classic model of grace and speed on land, is now an unlikely source of inspiration for more efficient flight. So says a group of University of Florida engineers who have recreated part of a unique bone in the horse’s leg with an eye toward lighter, stronger materials for planes and spacecraft.
The third metacarpus bone in the horse’s leg supports much of the force conveyed as the animal moves. One side of the cucumber-sized bone has a pea-sized hole where blood vessels enter the bone. Holes naturally weaken structures, causing them to break more easily than solid structures when pressure is applied. Yet while the third metacarpus does fracture, particularly in racehorses, it doesn’t break near the hole – not even when the bone is subjected to laboratory stress tests. UF engineering researchers think they’ve figured out why – and they’ve built and are testing a plate that mimics the bone’s uncanny strength in a form potentially useful for airplanes and spacecraft.

Researchers question authenticity of new malaria drug

A new investigation by The Scientist magazine reveals that some researchers believe the anti-malaria drug Malarex has not been adequately tested or, worse still, may be a fraud. The drug, touted by its Canadian manufacturer Millenia Hope as safe and effective, is already approved for sale by five African nations. However, respected researchers point to a serious lack of basic research on this drug, which is based on a herbal remedy.

Pot’s distant relative may be next prozac

Man-made chemicals that are distant relatives of marijuana may eventually become new drugs to combat anxiety and depression, according to a California study. The study is the first to show how anxiety is controlled by the body’s anandamide system, a network of natural compounds known for their roles in governing pain, mood and other psychological functions.

Tailor-made proteins manufactured in novel E. coli system

The prospect of using bacteria to manufacture complex human proteins for use in therapeutic drugs is a step closer thanks to new research published today in Science. Researchers from Switzerland and the UK report they have engineered the bacterium Escherichia coli to carry a vital piece of cell machinery that adds sugar molecules to newly synthesized proteins by a process known as glycosylation. The finding opens up the possibility of producing complex human proteins such as Factor VIII and the hormone erythropoietin, which stimulates the production of red blood cells by stem cells in bone marrow. Both these proteins, which require the addition of sugar molecules to function properly, are currently produced by culturing mammalian cells, which can be a costly and technically difficult process.