Marijuana use could cause tubal pregnancies

Marijuana use may increase the risk of ectopic (tubal) pregnancies, researchers at Vanderbilt University Medical Center reported this week. The researchers studied CB1, a ”cannabinoid” receptor that binds the main active chemical for marijuana, delta-9-tetrahydrocannabinol (THC). In pregnant mice that lacked the gene for the receptor, or in which the receptor was blocked, the embryo failed to go through the oviduct — the tube leading from the ovaries to the uterus. The same thing happened in normal mice when the receptor was over-stimulated.

Blacks significantly less likely to undergo prostate cancer screening

Although black men in the United States are more likely than white men to be diagnosed with advanced prostate cancer and have a two-fold greater risk of dying from it, they are significantly less likely to be screened for prostate cancer, according to a Dana-Farber Cancer Institute and Brigham and Women’s Hospital study. In a study involving more than 67,000 men age 65 years and older, the researchers found that blacks were 35 percent less likely than whites to undergo prostate-specific antigen (PSA) testing.

Vietnam vets had higher death rates after discharge than other veterans

Vietnam veterans had higher death rates in the first five years after discharge than veterans who did not serve in Vietnam, according to a new 30-year follow-up study. During the 1980s, the Centers for Disease Control and Prevention conducted the Vietnam Experience Study (VES) to look at the long-term health effects of military service in Vietnam. Serving in Vietnam exposed servicemen to several possible health factors, including exposure to psychological stress associated with war, infectious diseases prevalent in Vietnam, pesticides and herbicides, and drug and alcohol abuse. The original VES followed 18,313 US Army veterans from their date of discharge from active duty (1965-1977) through December 31, 1983. This study was somewhat limited by the young age of the participants (average age, 36.1 years) and the small number of deaths (446), the article states.

The mouse that soared

Astronomers have used an X-ray image to make the first detailed study of the behavior of high-energy particles around a fast moving pulsar. The image, from NASA’s Chandra X-ray Observatory, shows the shock wave created as a pulsar plows supersonically through interstellar space. These results will provide insight into theories for the production of powerful winds of matter and antimatter by pulsars.

Doh! New format could store all of Homer’s life on one optical disk

Physicists at Imperial College London are developing a new optical disk with so much storage capacity that every episode of The Simpsons made could fit on just one. Speaking at the Asia-Pacific Data Storage Conference 2004 in Taiwan today, Dr Peter T?r?k, Lecturer in Photonics in the Department of Physics, will describe a new method for potentially encoding and storing up to one Terabyte (1,000 Gigabytes) of data, or 472 hours of film, on one optical disk the size of a CD or DVD.

Knock knock knocking on rhythm’s neural doors

Drum the tip of a finger on a typewriter key quickly ”eeeeee.” Now, stop and type ”e” take a moment, type ”e,” take another moment, type ”e” again. The motion in both cases is exactly the same, performed by the same finger. But the brain processes that make the two different streams of ‘e’s are utterly different, according to a study done by a University of Southern California neural specialist and colleagues.

Fortifying food with folic acid benefits babies

Adding folic acid to food can dramatically reduce the incidence of spina bifida and other birth defects. A new study shows that the proportion of babies born with neural tube defects in the province of Newfoundland and Labrador dropped by 78% after the Canadian Government directed that folic acid must be added to flour, cornmeal and pasta. The study supports the continuation of this food fortification strategy.

Fat-derived stem cells improve heart function after heart attack

Adipose tissue (fat) derived regenerative cells improved heart function following myocardial infarction in a large-animal preclinical safety study. This study, performed in swine, confirms previous preclinical that the technology is safe and may be clinically useful in treating heart disease. The goal of the study was to determine the safety of adipose tissue-derived regenerative cells delivered into coronary circulation without cell culture.

Study reveals function of lipid in neuronal synapses

Researchers have demonstrates the crucial role of a membrane lipid called phosphatidylinositol-4,5-bisphosphate (PtdIns (4,5)P2) in the communication of information between synapses in the brain, according to a new study. ”This study is the first to show that lowering the levels of this lipid in nerve terminals affects the efficiency of neurotransmission,” said senior author, Pietro De Camilli. De Camilli’s laboratory has extensively studied the mechanism underlying cycling of synaptic vesicles, the small sacs containing neurotransmitters that exchange information between neurons. Synaptic vesicles release their contents at junctions between nerve terminals by fusing with the plasma membrane where they rapidly re-internalize, reload with neurotransmitter, and are reused.

Scientists successfully target key HIV protein

In what may be a first step toward expanding the arsenal against HIV, researchers have successfully targeted an HIV protein that has eluded existing therapies. Researchers targeted Nef, a protein responsible for accelerating the development of acquired immunodeficiency syndrome, or AIDS. Nef was targeted with small molecules synthesized by the researchers — molecules that disrupted Nef’s interaction with other proteins.

Imaging reveals anthrax’s secret to antibiotic resistance

Computer-generated images of a crucial anthrax bacterium enzyme are helping to solve the mystery of how slight mutations in the shape of this protein can make it resistant to the antibiotics called sulfa drugs. Based on these new insights into the structure of the enzyme, called DHPS, the researchers have also developed a new molecule that appears likely to be able to block the enzyme’s activity without triggering resistance.

Researchers identify T cell that relieves asthma in mice

For the second time in two years, scientists at the Stanford University School of Medicine have discovered a new type of regulatory T cell that reduces asthma and airway inflammation in mice, bolstering the theory that a deficiency of such cells is a prime cause of the breathing disorder as well as allergies. The team’s research not only provides a detailed profile of these newfound cells but also sheds light on how such cells are related to other T cells and suggests that there exists a spectrum of regulatory T cells, known as Tregs, to be identified and studied.

Fathers less likely to live with infants in poor health

A study of mainly unwed, U.S. urban parents finds that fathers of infants in poor health are less likely to be living with the child’s mother following the child’s first birthday than fathers of healthy children. The study, published in the latest issue of the journal Demography, also finds that having an infant in poor health decreases the chances a couple who had been living together (either married or cohabiting) at the time of the child’s birth still would be living together 12 to 18 months later. ”Within a very short period, having a child in poor health increased the likelihood the parents became less involved.”

Older Mexican-born Hispanics return to Mexico when ill

Mystery solved–at least in part. For almost two decades, demographers have puzzled over why U.S. Hispanics have lower mortality rates in adulthood than do non-Hispanic whites. Hispanics’ lower education and income levels should be linked to higher rates of illness and earlier death as they are for other racial and ethnic groups, but they aren’t.