Plague vaccine elicits 100% response in mice

A Canadian biomedical company said it has confirmed that a nasal vaccine protects mice against pneumonic Plague caused by lethal aerosol infection. In a series of experiments performed by the US Army Medical and Materiel Command at Fort Detrick, Maryland, in collaboration with ID Biomedical, mice nasally immunized with Plague antigen formulated with the Proteosome technology were completely protected against lethality (100%) even when the dose of Plague antigen was ten-fold lower than ever previously given nasally. In marked contrast, none of the control mice given nasal solution without vaccine antigen survived.

Current Funding Pattern Threatens Biomedical Research

Biomedical research and the development of powerful new diagnostic tools will be hobbled in the U.S. if the government fails to adequately fund mathematics, physics and engineering research, major drivers, of progress in biology, according to the executive director of the Institute for Quantitative Biomedical Research, headquartered at UCSF. Physics underlies powerful medical imaging diagnostics such as MRI and CAT capabilities, while mathematical tools are essential to tease apart complex signaling networks active in nearly all essential cell processes, said Marvin Cassman, PhD. “If we don’t adequately support physics, engineering and mathematics, we put the brakes on medically-related progress as surely as we slow advances in math and physics,” he said.