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Parkinson's symptoms shown on PET scans

A neurologist has used an advanced form of brain imaging to identify changes in small regions of the brains of living Parkinson’s disease patients for the first time. These scientists analyzed positron emission tomography (PET) scans of the brains of 41 Parkinson’s patients and 16 normal individuals obtained at the Hammersmith Hospital, part of the Imperial College of Medicine in London, England. The scans focused on two small areas found deep in the brain called the locus coeruleus and raphe, areas that control attention and wakefulness. The analysis found positive evidence of degeneration of nerve cells in these areas.

Sex, hormones & genetics affect brain's pain control system

We all know people who can take pain or stress much better than we can, and others who cry out at the merest pinprick. We’ve heard stories of people who did heroic deeds despite horrible injuries, and stereotypes about women’s supposedly sensitivity to pain that don’t mesh with their ability to withstand childbirth’s pain. But what accounts for all these differences in how individuals feel and respond to pain? And why are some people, especially women, more frequently prone to disorders – like temporomandibular joint pain and fibromyalgia – that cause them to feel crippling pain day and night?

Addicts’ Brains Work Harder to Control Behavior

A brain-imaging study conducted at the U.S. Department of Energy’s Brookhaven National Laboratory reveals that recently abstinent methamphetamine abusers who reported they avoided harmful situations had higher resting metabolic rates in a part of the brain responsible for making decisions and modifying behaviors than those with low harm-avoidance scores. In non-addicted, comparison subjects, there was no significant association between harm avoidance and metabolism in this brain region. The findings, reported in the December 3, 2002, issue of NeuroReport, suggest that this higher-level brain center — the orbitofrontal cortex — is involved in drug addiction, and might be working extra hard in addicts trying to stay off drugs.