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Mount Sinai researchers find new target to improve pain management

Researchers from Mount Sinai School of Medicine have discovered a major mechanism underlying the development of tolerance to chronic morphine treatment. The discovery may help researchers find new therapies to treat chronic pain, and reduce toleranc...

Major moral decisions use general-purpose brain circuits to manage uncertainty

CAMBRIDGE, Mass. -- Scientists at Harvard University have found that humans can make difficult moral decisions using the same brain circuits as those used in more mundane choices related to money and food. These circuits, also found in other anim...

Controlling Neurons May Ease Parkinson's Disease

Blocking or eliminating a specific potassium channel in a small group of brain cells may improve or prevent the symptoms of Parkinson's disease, a debilitating and progressive neurodegenerative disease that afflicts over 1 million people in the United States. In Parkinson's disease, neurons that release dopamine die. The loss of dopamine causes an array of debilitating symptoms that include resting tremor, muscle rigidity and slowed movement. Although the cause of the disease remains uncertain, James Surmeier and colleagues at Northwestern University have discovered a way of potentially lessening the symptoms and progression of the disease. The investigators describe their findings in the March issue of Nature Neuroscience.<

Controlling 'badly' behaving neurons may ease Parkinson's disease

Blocking or eliminating a specific potassium channel in a small group of brain cells may improve or prevent the symptoms of Parkinson's disease, a debilitating and progressive neurodegenerative disease that afflicts over 1 million people in the United States. In Parkinson's disease, neurons that release dopamine die. The loss of dopamine causes an array of debilitating symptoms that include resting tremor, muscle rigidity and slowed movement.

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