Skip to content
ScienceBlog.com
  • Featured Blogs
    • EU Horizon Blog
    • ESA Tracker
    • Experimental Frontiers
    • Josh Mitteldorf’s Aging Matters
    • Dr. Lu Zhang’s Gondwanaland
    • NeuroEdge
    • NIAAA
    • SciChi
    • The Poetry of Science
    • Wild Science
  • Topics
    • Brain & Behavior
    • Earth, Energy & Environment
    • Health
    • Life & Non-humans
    • Physics & Mathematics
    • Social Sciences
    • Space
    • Technology
  • Our Substack
  • Follow Us!
    • Bluesky
    • Threads
    • FaceBook
    • Google News
    • Twitter/X
  • Contribute/Contact

Cell nucleus

Researchers investigated the function of PQBP3, a protein that was previously linked to certain neurodegenerative diseases, and unveiled its role in maintaining the integrity of the nuclear membrane. In senescent (aged) cells, PQBP3 concentration is decreased thereby promoting Lamin B1 degradation, and PQBP3 leaks from its typical place in the nucleolus to the cytosol, which in turn causes the nuclear membrane to get destabilized.

Protein Discovery Illuminates Link Between Aging and Brain Diseases

Substack subscription form sign up

Comments

  • Curtis Webber on The GPS-Killer? This Quantum Device ‘Feels’ Motion Like a Brain—Down to the Atomic Level
  • Ran on How the Age You First Had Sex Could Shape How You Age Decades Later
  • Sparty on How the Age You First Had Sex Could Shape How You Age Decades Later
  • Josh Mitteldorf on A Single TV Segment Sent Leucovorin Prescriptions for Autistic Children Soaring 2,000 Percent
  • Josh Mitteldorf on A Single TV Segment Sent Leucovorin Prescriptions for Autistic Children Soaring 2,000 Percent
© 2026 ScienceBlog.com | Follow our RSS / XML feed