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clinical trials

Professor Charlotte Coles Credit: Patrick Harrison/Cancer Research UK

Radiotherapy Advance: New Trial Cuts Breast Cancer Treatment Time by a Week

Ozempic (Semaglutide) injectors

Higher Doses of Oral Semaglutide Show Improved Blood Sugar Control and Weight Loss

Placebo controls—gold standard for EFFICACY trials—have no place in SAFETY trials

Ketamine bottles

Ketamine nasal spray may prove safe and effective treatment for refractory migraine

blood brain barrier illustration

Tens of thousands of lives a year could be saved by new stroke treatment

Depressed young woman illustration

Ketamine as Effective as Electroconvulsive Therapy for Treatment-Resistant Depression

Hand holding a syringe

New Vaccine Shows Promise Against Meningococcal Disease

Northwestern Medicine scientists led by Adam Sonabend report results of the first in-human clinical trial using a skull-implantable ultrasound device to open the blood-brain barrier and repeatedly permeate large, critical regions of the human brain t...Show More Caption →

Chemotherapy drug reaches brain in humans for first time

Pathological phosphorylation (yellow) of Tau proteins (red-orange) leads to disintegration of microtubuli in the neuron axon an aggregation of the tau proteins. The transport of synaptic vesicles (orange-blue) is interrupted. Credit: selvanegra on iStock

First ‘gene silencing’ drug for Alzheimer’s disease shows promise

Blood bag for transfusion

Sex of blood donor has no effect on recipient survival

Control mice show the ability to clear away an experimental infection (images in the left column). But mice with impaired antimicrobial programs show increased intestine damage and inflammation (images in the right column), according to a study published in the Journal of Experimental Medicine.

Study to decode microbe-gut signaling suggests potential new treatment for IBD

Don Cleveland, PhD, Distinguished Professor of Medicine, Neurosciences and Cellular and Molecular Medicine at UC San Diego School of Medicine, is among the most highly cited researchers in the world for his work investigating neurodegenerative diseases.

DNA treatment could delay paralysis that strikes nearly all patients with ALS

Abnormal neural synchrony underlies many neurological conditions, including Parkinson’s disease, which can cause tremors. | iStock/Astrid860

New Focused Ultrasound Effective for treating Parkinson’s, Movement Disorders

Waist-up portrait of smiling Asian pregnant woman using modern laptop while working from home, cozy interior of living room on background

Single dose of common antibiotic reduces mothers’ risk of death during childbirth

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