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People with obsessions and compulsions experience considerable benefit from a combined treatment of drugs and behavioural therapy. Treatment with drugs alone is less effective. This is revealed in doctoral research by psychologist Nienke Tenney from Utrecht University. About half of the patients with an obsessive-compulsive disorder do not benefit from treatment. Some refuse treatment or stop the treatment before it has been completed. Moreover, many patients who do respond to treatment continue to experience a considerable number of residual symptoms.
Excessive bleeding, a troublesome side-effect that causes many women to stop taking hormone replacement therapies (HRT), is less likely with progesterone than with more commonly used synthetic versions. Results from a national clinical trial published in the November issue of the Journal of Obstetrics and Gynecology, show that a combination of estrogen and micronized progesterone (MP) causes fewer days and less intense bleeding than the most commonly used combination. Previous studies have shown that unacceptable bleeding is the reason that most women discontinue HRT during the first year of therapy.