New induced stem cells may unmask cancer at earliest stage

MADISON – By coaxing healthy and diseased human bone marrow to become embryonic-like stem cells, a team of Wisconsin scientists has laid the groundwork for observing the onset of the blood cancer leukemia in the laboratory dish.
“This is the first…

Small molecule may disarm enemy of cancer-fighting p53

ORLANDO — A pioneering clinical trial is testing the effectiveness in leukemia of a small molecule that shuts down MDM2, a protein that can disable the well-known tumor suppressor p53.
Michael Andreeff, M.D., Ph.D., professor of Medicine and ch…

Targeted agent shows promise for chronic lymphoid leukemia

COLUMBUS, Ohio — Researchers at the Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James) have identified an experimental agent that targets chronic lymphocytic l…

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