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Opioid crisis

Naloxone nasal spray

Study Reveals Surge in Layperson Naloxone Use, but More Action Needed to Combat Opioid Crisis

NbE (red) binds the specific receptor responsible for opioid action (blue) and blocks off other small molecules (white/yellow/red).

Nanobody Offers Hope in Combating Opioid Side Effects and Overdoses

Naloxone nasal spray

New Compound Boosts Overdose-Reversing Drug’s Power

Legacy of federal opioid intervention: communities equipped to act

stack of documents sitting on a desktop

Revealed: tricks used by opioid giant to mold doctors’ minds

Fentanyl

A quarter of deaths among young adults in Canada were opioid related in 2021

Opioid treatment illustration

Treating opioid disorder without meds more harmful than no treatment at all

Pills

Prescribing just a few opioid tablets to patients discharged from emergency departments can ease pain but prevent misuse

A simplified schema of the four waves of the US overdose mortality crisis. Waves 1 and 2 include deaths involving commonly prescribed opioids, and heroin, respectively, but excluding fentanyl co-involved deaths. Wave 3 and Wave 4 show fentanyl deaths not involving, and involving, stimulants respectively as distinct trends. Data from CDC WONDER.

The fourth wave of the US overdose crisis: fentanyl and stimulants

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