Skip to content
ScienceBlog.com
  • Featured Blogs
    • EU Horizon Blog
    • ESA Tracker
    • Experimental Frontiers
    • Josh Mitteldorf’s Aging Matters
    • Dr. Lu Zhang’s Gondwanaland
    • NeuroEdge
    • NIAAA
    • SciChi
    • The Poetry of Science
    • Wild Science
  • Topics
    • Brain & Behavior
    • Earth, Energy & Environment
    • Health
    • Life & Non-humans
    • Physics & Mathematics
    • Social Sciences
    • Space
    • Technology
  • Our Substack
  • Follow Us!
    • Bluesky
    • Threads
    • FaceBook
    • Google News
    • Twitter/X
  • Contribute/Contact

SiRNA

In the brain's immune cells, called microglia, the gene product PU.1 is associated with excessive inflammation in neurological disorders such as Alzheimer's disease. MIT researchers delivered a small interfering RNA (siRNA) via lipid nanoparticles to reduce expression of PU.1 in mice. Microglia stained for PU.1 or related markers are less evident in the bottom row, which reflects the effects of the siRNA, compared to an experimental control (top row).

Nanoparticles Target Brain Cells to Quell Alzheimer’s Inflammation

Substack subscription form sign up

Comments

  • Norwood johnson on Electrons in New Crystals Behave as If They Live in Four Dimensions
  • ScienceBlog.com on Hidden Geometry Could Finally Fix Quantum Computers
  • Theo Prinse on America Is Going Back to the Moon. This Time, It Plans to Stay
  • george w on Hidden Geometry Could Finally Fix Quantum Computers
  • Tom Hughes on Years of Exercise, Blood Pressure Drugs Failed to Slow Cognitive Decline in Seniors at Dementia Risk
© 2026 ScienceBlog.com | Follow our RSS / XML feed