Researchers probe possible Strep, Obsessive-Compulsive Disorder link

A new study aims to determine once and for all whether a link exists between obsessive-compulsive behavior and strep infections in children. The research, to be conducted by the University of Florida and the National Institutes of Mental Health, is prompted by anecdotal reports from parents with OCD kids that their children’s behavior, such as compulsive hand washing, worsens when the child is ill with strep.

Fat cells converted to bone

Pre-cells destined to become fat can be converted instead into true bone cells in
response to outside signals, say researchers at the University of California, San Francisco. The finding could pave the way for scientists to replenish lost bone cells in patients with conditions like osteoporosis, and to help repair bone defects. The new bone cells have all the hallmarks associated with mature bone formation, including production of bone proteins and calcification, the UCSF team says.

Parkinson’s patients look to gene therapy

Medical researchers have successfully reversed the progression of Parkinson’s disease in rats through the use of gene therapy. By adding a gene for a single enzyme, they were able to reprogram brain circuits and halt the deterioration of dopamine-producing brain cells, one of the key problems in the disease. The lack of dopamine is what leads the the tell-tale shaking and muscle twitches of Parkinson’s patients.

Dinosaur mummy sheds light on look, feel of prehistory

Turns out all those CGI cats working on the “Jurassic Park” and “Lost World” films were pretty spot on. A mummified dinosaur uncovered in Montana looks shockingly like the creatures depicted on the big screen. Almost too much alike. Hey, wait a minute….

You go, Jimmy!

The Norwegian Nobel Committee has decided to award the Nobel Peace Prize for 2002 to Jimmy Carter, for his “decades of untiring effort to find peaceful solutions to international conflicts, to advance democracy and human rights, and to promote economic and social development.”

Researchers Elucidate Machinery of Major Anti-Cancer Drug Target

Researchers have detailed the functioning of an enzyme that is a central component of a signaling pathway important for about 30 percent of cancers. The findings about how the enzyme, called farnesyl transferase (FTase), works could help improve the FTase-inhibiting drugs that pharmaceutical companies are now testing to fight a broad spectrum of cancers.

Eczema all about infection

Researchers say they’ve found that people with atopic dermatitis, a.k.a. eczema, are susceptible to bacterial infections in their skin because their bodies don’t produce enough of two antimicrobial peptides. The findings show that while an allergic reaction can cause a rash, true eczema is all about infection. And medicines containing or inducing the peptides could be used to fight the disorder, which affects millions worldwide.

In case you were wondering

The Wisconsin Department of Health and Human Services has published a four-point guide to hand washing. This is not a comment on the brain capacity of those in the “Forward” state, but rather a reminder of the single best way to fend off illness.

The steps are:
1. Wet your hands, ideally with very warm water.
2. Add soap, then rub your hands together to make a soapy lather. Vigorously scrub the front and back of your hands, between your fingers and under your nails, for no less than 10 seconds before you …
3. Rinse the lather off your hands, letting the water run into the sink, not down your arms.
4. In public restrooms, use a paper towel to turn off the water so you don’t touch a potentially-dirty handle, then …
5. Dry your hands thoroughly with a clean towel.

All right, it’s a five-point plan. Math never was Wisconsin’s strong suit. But, ummm, the cheese….

Vlad the Impaler defeats Fritz the Ditz

Maybe Deep Fritz should be called On the Fritz. The German-built, chess-playing computer lost another game to 27-year-old Russian champ Vladimir Kramnik in a match billed as the “Brains of Bahrain.” The competition’s third day of play ended when Kramnik, well, kicked Fritz’ butt in 57 moves that showed DNA can still best silicon at some things. As reported by Reuters, Sunday’s game wasn’t completely one-sided. “Fritz, after early errors, fought back and startled Kramnik with some typical computer tactics. ‘I never imagined (the 27th move) and the tactics that followed. Only a computer would find and play something like that,’ Kramnik said later. ‘I was completely shocked.’ The Fritz team was more than a little embarrassed, however, when their brainchild in move 12 returned its bishop to its original square. This bizarre move was something even the lowliest human player would never consider.”

Do you see the key?

If a code is really good, it doesn’t matter much if the enemy (you know, them) gets ahold of one of your encrypted messages. What is risky, is letting your code key fall into the wrong hands. And their delivery is often the weak link in a communications network. “At the moment, highly secure encryption keys are typically sent by a man on a motorbike or a guy with a diplomatic bag,” notes one wonk. But researchers have devised a way to deliver keys using a beam of light, attaching data to individual photons as they stream from sender to receiver. The neat thing about that is if the light beam is intercepted and read, the state of the photons changes, alerting the recipient that the key has been compromised. Thursday British researchers said they’d reached a new milestone in the distance they can send encryption keys this way: 14 miles. It doesn’t sound like much, but it sure beats the few feet the technique could muster just a couple years ago. Expect earth-to-satellite distances soon.

His Blue Period

No red, no white, but plenty of blue. That’s the strange ? make that straight-up freaky ? but true story of a sexagenarian Montana Congressional candidate who managed to permanently turn his own skin the color of the sea. The Associated Press reports that back in 1999, Stan Jones, a business consultant and part-time college instructor currently running for U.S. Senate under the Libertarian Party banner, began brewing and drinking a homemade colloidal silver potion. He did this, the wire service notes, because he feared a Y2K-related shortage of antibiotics. He apparently did not anticipate one side effect: his epidermis becoming a primary color….ScienceBlog bonus historical precedent: the famous Blue People of Kentucky.

Research that matters

New Scientist reports on a year-long study to find the world’s funniest joke. The Internet-based project was coordinated by psychologist Richard Wiseman and colleagues at the University of Hertfordshire, U.K. and involved more than 2 million votes on 40,000 submissions. The goal was to identify universal aspects to humor, which could one day allow computers to devise truly funny jokes. Before we get to the winner, an interesting aside is that the team found in the process the world’s funniest animal: the duck. “If you’re going to tell a joke involving an animal, make it a duck,” Wiseman says. Now to the ultimate rib-tickler, which folks from Asia to Africa, the States to Siberia all seemed to enjoy. A couple of New Jersey hunters are out in the woods when one of them falls to the ground. He doesn’t seem to be breathing, his eyes are rolled back in his head. The other guy whips out his cell phone and calls the emergency services. He gasps to the operator: “My friend is dead! What can I do?” The operator, in a calm soothing voice, says: “Just take it easy. I can help. First, let’s make sure he’s dead.” There is a silence, then a shot is heard. The guy’s voice comes back on the line. He says: “OK, now what?” Thank you folks, I’ll be here all week.

Scientists Decipher Genetic Code of Malaria Parasite

FROM THE TRENCHES: A consortium of scientists announced that it has deciphered the genetic code of the parasite that causes the deadliest form of Malaria, an illness that kills more than a million people a year in developing nations.

Facing disfigurement in 2002

With all the discussion about possible smallpox bioterrorism attacks in the U.S., has the dermatology world begun to address the cosmetic implications that an outbreak would entail? Sure, it sounds petty when lives are at stake. But if thousands of people stand to potentially become infected, has medicine developed any better means of preventing disfigurement? Drainage? Lots and lots of aloe gel? Sedatives to keep people doped until the pustules pass?

See also:
>>Preparing for smallpox
>>When rashes kill
>>Smallpox immunity lasts longer than thought
>>Mass smallpox vaccination plan urged