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Aging

older male exercising

Active Seniors Outsmart Mental Fatigue While Sedentary Peers Struggle

heart attack illustration

Heart Failure Accelerates Brain Aging by 10 Years, New Study Reveals

fat tailed dwarf lemur

Hibernating Lemurs Turn Back Time at Cellular Level

synthetic blood platelets

AI Model Predicts Biological Age from a Tiny Blood Sample

Evidence mounts that a long-term diet high in fat is not healthy.

Memory is impaired in aged rats after 3 days of high-fat eating

Aging man smiling on a park bench

Your Lifestyle, Not Your Genes, May Be the Biggest Factor in How Long You Live

Only CS genes were available for co-option and utilization for xanthine alkaloid biosynthesis in yerba mate whereas coffee only had xanthine methyltransferase (XMT) genes. Both CS- and XMT-type caffeine biosynthetic enzymes were present in the ancestor of core eudicots but numerous apparent losses of one or the other or both has occurred during lineage diversification. Gene loss is represented by vertical bar on relevant branches of the cladogram.

Scientists Map Fountain of Youth Genes in Ancient South American Tea Plant

Using patient data from several banks of genomics data, researchers at UC San Diego were able to make similar predictions of aging using either mutations or epigenetic modifications. Their results reveal a common link between two separate but equally prominent theories of aging.

Cracking the Code of Aging: Study Unites Two Rival Theories, Redefining Anti-Aging Science

HGF nitration disrupts muscle homeostasis as an organism age. The new rat anti-HGF monoclonal antibody the research team developed, called 1H41C10, specially binds to the nitration sites of HGF and blocks nitration. The team hopes that this can eventually lead to therapies that can treat age-related muscle atrophy and impaired muscle regeneration.

Researchers Develop Antibody to Combat Age-Related Muscle Atrophy

Woman on a Zoom call

Millennials’ Sedentary Lifestyle Accelerates Aging, Even With Regular Exercise

Pictures taken with a confocal microscope of the gut of drosophila (fruit fly) show enteroendocrine cells that express the NPF neuropeptide. Image courtesy of Marc Tatar.

Researchers show how gut hormones control aging in flies and how it relates to human biology

When the protein STING (pink) is activated, the transcription factor TFEB (green) is shuttled into the nucleus where it stimulates the production of lysosomes

STING Protein Plays Dual Role in Cellular Health and Aging, Pitt Study Finds

stacked, frozen fish at a market

Fish Gut Bacteria Yield Promising Compounds for Anti-Aging Skincare

Researchers investigated the function of PQBP3, a protein that was previously linked to certain neurodegenerative diseases, and unveiled its role in maintaining the integrity of the nuclear membrane. In senescent (aged) cells, PQBP3 concentration is decreased thereby promoting Lamin B1 degradation, and PQBP3 leaks from its typical place in the nucleolus to the cytosol, which in turn causes the nuclear membrane to get destabilized.

Protein Discovery Illuminates Link Between Aging and Brain Diseases

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