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drug development

Cone snail toxin (Conkunitzin-S1, shown in orange) interacting with a fish potassium channel (shown in blue). Courtesy of Eitan Reuveny and Izhar Karbat.

Cone snail toxin inspires new method for studying molecular interactions

Categories Life & Non-humans
Three-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image by NIH

One Shot Wonder: New Drug Eliminates Large Breast Tumors with Single Dose

Categories Health
Leishmaniasis on a human hand

Brazilian Plant Shows Promise Against Deadly Tropical Disease Leishmaniasis

Categories Health
ACM, the Association for Computing Machinery, named an eight-member team drawn from Australian and American institutions as the winner of the 2024 ACM Gordon Bell Prize.

Supercomputer Team Achieves Unprecedented Molecular Simulation Scale, Breaking Two Major Barriers

Categories Life & Non-humans, Technology
The brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell and degenerate due to the Tau protein. The red shows where Tau is building up in clusters along the neurons, starting to form the clumps that eventually become rope-like fibrils.

Promising ‘first’ in Alzheimer’s drug development

Categories Brain & Behavior
Ohio State logo

Novel chemical tool aims to streamline drug-making process

Categories Technology
structure of CNDR-51997

NIH Awards $6.9 Million to Advance Promising Alzheimer’s Treatment

Categories Brain & Behavior
A cityscape of a hazy morning

New Drug Shows Promise in Protecting Against Air Pollution-Linked Alzheimer’s Risk

Categories Brain & Behavior, Earth, Energy & Environment, Life & Non-humans
ZTA-261, a highly selective and less toxic THRβ agonist, is a promising candidate to improve lipid metabolism.

New Thyroid Hormone Drug Shows Promise for Treating Lipid Disorders with Fewer Side Effects

Categories Health
Lead study author Woong-Ki Kim, PhD, associate director for research at Tulane National Primate Research Center. Photo by Sabree Hill.

Promising New Drug Could Clear HIV from the Brain, Tulane Study Reveals

Categories Brain & Behavior, Health
A slide under a microscope with a blood sample

Blood proteins predict the risk of developing more than 60 diseases

Categories Health
WeGovy semaglutide

New research demonstrates potential for increasing effectiveness of popular diabetes, weight-loss drugs

Categories Health
A woman clutching her stomach and looking surprised

New Discovery Could Eliminate Nausea from Popular GLP1 Weight Loss Drugs

Categories Brain & Behavior, Health
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