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neurodegenerative diseases

Researchers demonstrate exosomes loaded with fluorescent sensors that can pass through the blood-brain barrier (BBB) where the sensors light up in the presence of neurotransmitters linked to Alzheimer’s disease in the brain.

Improving Alzheimer’s disease imaging — with fluorescent sensors

Categories Brain & Behavior, Health, Technology

Truck wheels on road in motion

Tiny Particles from Traffic Pollution Disrupt Brain Cell Function

Categories Brain & Behavior

Rugby players

New Blood Test Could Predict Neurodegenerative Risk in Retired Rugby Players

Categories Brain & Behavior, Health

Astrocytes. Credit: Dr Alice Braga, co-author of the Nature paper

Brain’s Energy Boost Mechanism Uncovered, Offers Hope for Late-Life Cognitive Health

Categories Brain & Behavior

Mutations in the presenilin gene, PSEN1, causes early onset of Alzheimer’s disease in humans and in fruit flies modified to have this gene. A new study led by researchers at Penn State revels that disrupting heparan sulfate–modified proteins in fruit flies suppressed neuronal death and corrected other cell deficits common in early stages of Alzheimer’s and other neurodegenerative diseases. Pictured here are full fruit fly brains, stained with a marker that indicates cell death—brighter colors indicate higher presence of cell death. Top: A fly with deficits in the presenilin gene—a model for Alzheimer’s disease—with high levels of cell death. Bottom: A fly rescued by disrupting heparan sulfate–modified proteins.

Potential new target for early treatment of Alzheimer’s disease

Categories Brain & Behavior

brain illustration

Researchers identify vascular changes in the brain linked to Alzheimer’s disease

Categories Brain & Behavior

A lab worker holding a vial of blood

Blood Test Detects Common Forms of Frontotemporal Dementia, ALS, and PSP

Categories Brain & Behavior

Protein clump amid neurons

The vicious cycle of protein clumping in Alzheimer’s and normal aging

Categories Brain & Behavior, Health

A microscopic view of neurons with a glowing molecule representing the miR-519a-3p biomarker, offering hope for early Alzheimer's detection.

MicroRNA Biomarker Offers Hope for Early Alzheimer’s Detection

Categories Brain & Behavior, Technology

a human head with a transparent brain, revealing a glowing compass-like structure within the hippocampus and surrounding regions.

Scientists Discover Internal Neural Compass in the Human Brain

Categories Brain & Behavior

Inhibition of an ESI1 target promotes oligodendrocyte myelin production in mice, as shown as a dense curtain of green strands. This small molecule shows early promise as a potential treatment for MS, and to manage aging-related nerve sheath deterioration, according to study led by experts at Cincinnati Children's.

Breakthrough Treatment Reverses Myelin Damage in Multiple Sclerosis, Study Finds

Categories Brain & Behavior, Health

brain oxidation and tocotrienols infographic

Natural Compounds Show Promise in Protecting the Brain from Obesity-Related Cognitive Decline

Categories Brain & Behavior, Health

garage with stored chemicals

Storing Chemicals in Attached Garages Linked to Higher Risk of ALS

Categories Brain & Behavior, Health

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