A vaccination against tuberculosis (TB) could be made more effective by injecting it directly into the bloodstream at a higher dose, new research suggests.
TB, caused by Mycobacterium tuberculosis, is one of the leading causes of infection globally, killing approximately 1.7 million people and infecting around 10 million annually. So far, the only licensed vaccine to fight this disease is the bacille Calmette-Guérin (BCG) vaccine, containing a weakened form of TB found in cattle. This vaccine is normally given to infants by injecting under the skin, or intradermally, to protect them against various types of TB. However, it isn’t very effective