Paean to NAC
Long before NAC saved the life of someone dear to me, it was a staple of my supplement stack.
Jun 7, 2021
Aging & evolutionary biology
Josh Mitteldorf is best known for promoting the theory that aging is not “wearing out” but rather an evolved program that limits lifespan. The surprising fact that our bodies are genetically programmed to age and to die offers an enormous opportunity for medical intervention. He began blogging about aging on this site in 2012. His guidance for a long life is at AgingAdvice.org. His two books on aging are available at Amazon and elsewhere.
Mitteldorf’s PhD is in astrophysics. Since about 2020, he has taken up a new challenge as curator and critic of science on the fringe, writing about promising science that the science establishment has unjustly neglected.
In other areas of life, Mitteldorf’s two daughters were among the first girls to be adopted from China in the 1980s. He has taught a weekly yoga class for fifty years. He is an avid amateur musician, playing piano in chamber groups, French horn in community orchestras. Follow his other writing at mitteldorf.substack.com, and listen to his poetry on YouTube.
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Long before NAC saved the life of someone dear to me, it was a staple of my supplement stack.
Jun 7, 2021

“Individuals with COVID-19 experience a vast number of neurological symptoms, such as headaches, ataxia, impaired consciousness, hallucinations, stroke and cerebral hemorrhage.
May 9, 2021
I recently wrote an April Fool piece about an imaginary drug company that invested a billion dollars in a COVID vaccine, but when they ran it through Phase 3 clinical trials it fell just short of statistical significance for effectiveness.
Apr 27, 2021
The paradox: In animal models there is a consistent relationship between eating less and living longer.
Mar 21, 2021
Caloric restriction is the gold standard life extension strategy, validated over thousands of experiments in many animal species.
Mar 9, 2021

A new methylation clock works in 128 different mammal species, using the same methylation signals.
Jan 24, 2021

Just as the melody is not made up of notes nor the verse of words nor the statue of lines, but they must be tugged and dragged till their unity has been scattered into these many pieces, so with the World to whom I say Thou.
Dec 31, 2020

Aging clocks = algorithms that compute biological age from a set of measurable markers.
Dec 21, 2020
This week, Deep Mind, a London-based Google company, claims to have solved the number one most consequential problem in computational biochemistry: the protein-folding problem.
Dec 3, 2020

An Israeli study came out last week that has been described as rejuvenation via hyperbaric oxygen.
Nov 25, 2020
I am heartened that the tide seems to be turning. The Great Barrington Declaration is attracting thousands of scientists’ signatures each day.
Oct 9, 2020
“Trials show low strength of evidence for no positive effect on intubation or death and discharge from the hospital, whereas evidence from cohort studies about…
Oct 6, 2020