Health
Rumors of Age Reversal: The Plasma Fraction Cure
I say “rumors” because there is no publication and results from just 6 rats, all of which were sacrificed for the sake of tissue biopsies.
Feb 5, 2019
Column
Josh Mitteldorf
Aging & evolutionary biology
Josh Mitteldorf is best known for promoting the theory that aging is not “wearing out” but rather an evolved program that limits lifespan. The surprising fact that our bodies are genetically programmed to age and to die offers an enormous opportunity for medical intervention. He began blogging about aging on this site in 2012. His guidance for a long life is at AgingAdvice.org. His two books on aging are available at Amazon and elsewhere.
Mitteldorf’s PhD is in astrophysics. Since about 2020, he has taken up a new challenge as curator and critic of science on the fringe, writing about promising science that the science establishment has unjustly neglected.
In other areas of life, Mitteldorf’s two daughters were among the first girls to be adopted from China in the 1980s. He has taught a weekly yoga class for fifty years. He is an avid amateur musician, playing piano in chamber groups, French horn in community orchestras. Follow his other writing at mitteldorf.substack.com, and listen to his poetry on YouTube.
Search Josh Mitteldorf’s columns only
Results stay inside this archive — not the rest of Science Blog.
Health
Denial of Death or Denial of Immortality
At year end, I have a tradition of writing a column more speculative and personal than usual.
Dec 30, 2018
Health
The Body Electric
Aging is an extension of the developmental program into a phase of self-destruction.
Dec 21, 2018
Health
Letter to an Incipient Cancer Survivor
This is a letter I wrote to a dear friend from the 1970s who has been diagnosed recently with colon cancer.
Nov 14, 2018
Health
Fisetin—a new senolytic
Senolytic drugs have been the most promising near-term anti-aging therapy since the ground-breaking paper by van Deursen of Mayo Clinic published in 2011. The…
Oct 23, 2018
Health
A cure for Alzheimer’s? Yes, a cure for Alzheimer’s!
This is the most important column I’ve ever written. The message is quite complex--dozens of new health parameters to test for and to optimize, all of them interacting in ways that will require new training for MDs.
Oct 15, 2018
Health
Aubrey & Me
I’ve been in the field of aging research from the late 1990s, just the time when Aubrey de Grey was getting his start.
Oct 8, 2018
Health
Chinese Longevity Herb
Fo-ti is a root herb from traditional Chinese medicine that has been used for centuries as an anti-aging tonic, and has shown promise in limited Western-style analyses.
Sep 24, 2018
Health
If you’re over 50, don’t stop taking aspirin
This week, a headline-making study in the New England Journal of Medicine sought to cast doubts on long-established science that says daily aspirin can be a broadly-effective anti-aging tonic.
Sep 18, 2018
Health
Heat shock / Cold shock
Heat Shock Protein [My sources for much of this article are a 2018 review from University of Campinas, Brazil and a 2016 review on hormesis by Joan Smith…
Aug 26, 2018
Health
The Most Effective Personal Anti-aging Program
What are the most effective things you can do to slow the aging process and extend your life expectancy?
Aug 2, 2018
Health
Alpine Apnea and Aging
The Mother of All Clinical Trials, which I announced in April, continues to progress at a charmed pace.
Jul 2, 2018