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Michael Corley, PhD, associate professor of medicine in the Division of Geriatrics, Gerontology & Palliative Care at UC San Diego School of Medicine and the Stein Institute for Research on Aging.

Weight-Loss Drug Semaglutide Slows Markers of Biological Aging in First Randomized Human Trial

woman lifting weights

Two Hours a Week of Strength Training Lowers Your Risk of Death, and More Is No Better

teen girl vaping

On TikTok, an Illegal Vape Arrives Disguised as Lip Gloss

Man looking anxious

Why Fixing a Person’s Sleep Might Also Lift Their Depression

Obese Woman with fat belly in dieting concept. Overweight woman touching his fat belly and want to lose weight. Fat woman her waist with a centimeter. Shape up healthy stomach muscle and diet lifestyle concept.

Weight Loss Drug Revolution Could Leave Britain’s Poorest Patients Behind

Researchers reveal that gut microbiota metabolizes selenium into products that influence detoxification and excretion.

Gut Microbes Help Decide How Much Selenium Your Body Keeps

Cancer cells

Vaccine Built From Person’s Tumor Is Still Holding Melanoma Back Five Years On

Alcohol-induced mitochondrial changes in liver disease. (A) Human Liver: Staining from a patient with alcohol-associated hepatitis. (B) Mouse Liver: Electron microscopy after alcohol feeding. Arrows show abnormally enlarged mitochondria (megamitochondria). Scale bars: 100 μm (A), 500 nm (B). (C) Mechanism: Alcohol reduces the protein DRP1, stopping normal mitochondrial splitting (fission) and trapping mitochondria in an inactive state (stasis, gray module). Disease Progression: While new megamitochondria temporarily protect the liver by boosting metabolism, chronic alcohol exposure destroys this defense. The damaged mitochondria then leak signals that trigger cell death, severe inflammation (via cGAS–STING), and abnormal cell growth, ultimately driving liver injury and tumors.

Why Some Heavy Drinkers Grow Giant Mitochondria That Guard the Liver, for a While

Justicia carnea

A Garden Shrub Known as Blood Tonic Shielded Mouse Pancreas Cells From Inflammatory Damage

female practicioner

80,000 Doctors and Nurses Caught in America’s Broadest Immigration Ban

modern home with For Sale sign in front

Pandemic Loan Fraud Helped Push Up US House Prices, and Ordinary Buyers Paid for It

A mini version of the connected human brain and spinal cord system created in the lab.

A Contraceptive Drug May Help Reverse Nerve Damage Once Thought Permanent

nanofiber mesh between fingers of a gloved hand

A Tiny Drug-Loaded Mesh Implanted in the Brain Is Keeping Glioblastoma at Bay

man grasping painful knee

The Molecule Our Own Cells Make That Could Finally Help Treat Drug-Resistant Rheumatoid Arthritis

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